2-amino-5-phosphonovalerate has been researched along with Glial Cell Tumors in 3 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found in cultured glioma (C6BU-1) cells that excitatory amino acids (EAAs) such as glutamate, N-methyl-D-aspartate (NMDA), aspartate, and metabotropic glutamate receptor agonist trans-(+/-)-1-amino-1,3-cyclopentanedicarboxylate caused an increase in the inositol 1,4,5-trisphosphate formation and the intracellular Ca2+ concentration ([Ca2+]i) in the absence of extracellular Mg2+ and Ca2+." | 3.69 | Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction. ( Mikuni, M; Saitoh, K; Shinno, H; Takahashi, K; Tomita, U; Yamawaki, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johansson, T | 1 |
| Elfverson, M | 1 |
| Birgner, C | 1 |
| Frändberg, PA | 1 |
| Nyberg, F | 1 |
| Le Grevès, P | 1 |
| Shinno, H | 1 |
| Mikuni, M | 1 |
| Saitoh, K | 1 |
| Tomita, U | 1 |
| Yamawaki, S | 1 |
| Takahashi, K | 1 |
| Amano, T | 1 |
| Yamakuni, T | 1 |
| Okabe, N | 1 |
| Kuwahara, R | 1 |
| Ozawa, F | 1 |
| Hishinuma, F | 1 |
3 other studies available for 2-amino-5-phosphonovalerate and Glial Cell Tumors
| Article | Year |
|---|---|
Neurosteroids alter glutamate-induced changes in neurite morphology of NG108-15 cells.
Topics: 2-Amino-5-phosphonovalerate; Cell Adhesion; Cell Line, Tumor; Excitatory Amino Acid Agonists; Glioma | 2007 |
Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cell Line; Cycloleucine; Dizocilpine M | 1994 |
Regulation of nerve growth factor and nerve growth factor receptor production by NMDA in C6 glioma cells.
Topics: 2-Amino-5-phosphonovalerate; Animals; Base Sequence; Blotting, Northern; Bucladesine; Cyclic AMP; Gl | 1992 |