2-amino-5-phosphonovalerate has been researched along with Diathesis in 6 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Seizures were evoked with bicuculline (3." | 7.70 | The influence of CGP-40116 on bicuculline evoked seizures in mice exposed to transient episode of brain oligemia. ( Czuczwar, SJ; Kleinrok, Z; Rejdak, K; Rejdak, R; Sieklucka-Dziuba, M, 2000) |
| " Motor limbic seizures induced by pilocarpine, 380 mg/kg intraperitoneally, are prevented by prior injection into the substantia nigra, pars reticulata, or the entopeduncular nucleus, of 2-APH, 10 nmol or 10 pmol, respectively." | 4.77 | Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists. ( de Sarro, G; Meldrum, B; Millan, M; Patel, S, 1988) |
| " Seizures were evoked with bicuculline (3." | 3.70 | The influence of CGP-40116 on bicuculline evoked seizures in mice exposed to transient episode of brain oligemia. ( Czuczwar, SJ; Kleinrok, Z; Rejdak, K; Rejdak, R; Sieklucka-Dziuba, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Norris, CM | 1 |
| Korol, DL | 1 |
| Foster, TC | 1 |
| Di Loreto, S | 1 |
| Balestrino, M | 1 |
| Rejdak, K | 1 |
| Rejdak, R | 1 |
| Czuczwar, SJ | 1 |
| Kleinrok, Z | 1 |
| Sieklucka-Dziuba, M | 1 |
| Yang, L | 1 |
| Long, C | 1 |
| Faingold, CL | 1 |
| Golarai, G | 1 |
| Greenwood, AC | 1 |
| Feeney, DM | 1 |
| Connor, JA | 1 |
| Meldrum, B | 1 |
| Millan, M | 1 |
| Patel, S | 1 |
| de Sarro, G | 1 |
1 review available for 2-amino-5-phosphonovalerate and Diathesis
| Article | Year |
|---|---|
Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Disease Su | 1988 |
5 other studies available for 2-amino-5-phosphonovalerate and Diathesis
| Article | Year |
|---|---|
Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Calcium; Disease Susceptibility; In Vitro Techniques; L | 1996 |
Development of vulnerability to hypoxic damage in in vitro hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Disease Susceptibility; Embryo, Mammalian; Embryonic and Fetal | 1997 |
The influence of CGP-40116 on bicuculline evoked seizures in mice exposed to transient episode of brain oligemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Convulsants; D | 2000 |
Audiogenic seizure susceptibility is induced by termination of continuous infusion of gamma-aminobutyric acid or an N-methyl-D-aspartic acid Antagonist into the inferior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Behavior, Animal; Catheterization; Disea | 2001 |
Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Injuries; Cell Count; Cell Death; Chronic Disease; Denta | 2001 |