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2-amino-5-phosphonovalerate and Delayed Effects, Prenatal Exposure

2-amino-5-phosphonovalerate has been researched along with Delayed Effects, Prenatal Exposure in 9 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Research Excerpts

ExcerptRelevanceReference
"Maternal cigarette smoking during pregnancy and maternal nicotine exposure in animal models are associated with cognitive impairments in offspring."3.83Early postnatal nicotine exposure disrupts the α2* nicotinic acetylcholine receptor-mediated control of oriens-lacunosum moleculare cells during adolescence in rats. ( Chen, K; Nakauchi, S; Su, H; Sumikawa, K; Tanimoto, S, 2016)
"Nicotine SA was augmented in adolescent Nic + EtOH versus PF offspring (p = 0."1.40Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats. ( Chen, H; Matta, SG; Roguski, EE; Sharp, BM, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roguski, EE1
Sharp, BM1
Chen, H1
Matta, SG1
Collison, KS1
Inglis, A1
Shibin, S1
Andres, B1
Ubungen, R1
Thiam, J1
Mata, P1
Al-Mohanna, FA1
Luebke, J1
St John, J1
Galler, JR1
Chen, K1
Nakauchi, S1
Su, H1
Tanimoto, S1
Sumikawa, K1
Sadowski, RN1
Stebbings, KA1
Slater, BJ1
Bandara, SB1
Llano, DA1
Schantz, SL1
Kamendi, HW1
Cheng, Q1
Dergacheva, O1
Gorini, C1
Jameson, HS1
Wang, X1
McIntosh, JM1
Mendelowitz, D1
Zhou, R1
Zhang, Z1
Zhu, Y1
Chen, L2
Sokabe, M1
Samudio-Ruiz, SL1
Allan, AM1
Valenzuela, CF1
Perrone-Bizzozero, NI1
Caldwell, KK1
Escobar, M1
Crouzin, N1
Cavalier, M1
Quentin, J1
Roussel, J1
Lanté, F1
Batista-Novais, AR1
Cohen-Solal, C1
De Jesus Ferreira, MC1
Guiramand, J1
Barbanel, G1
Vignes, M1

Other Studies

9 other studies available for 2-amino-5-phosphonovalerate and Delayed Effects, Prenatal Exposure

ArticleYear
Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats.
    Journal of neurochemistry, 2014, Volume: 128, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Central Nervous System Depressants; Chromat

2014
Differential effects of early-life NMDA receptor antagonism on aspartame-impaired insulin tolerance and behavior.
    Physiology & behavior, 2016, 12-01, Volume: 167

    Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Aspartame; Behavior, Animal; Blood Glucose;

2016
Prenatal protein malnutrition results in increased frequency of miniature inhibitory synaptic currents in rat CA1 pyramidal cells.
    Synapse (New York, N.Y.), 2000, Volume: 37, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animal Nutritional Physiological

2000
Early postnatal nicotine exposure disrupts the α2* nicotinic acetylcholine receptor-mediated control of oriens-lacunosum moleculare cells during adolescence in rats.
    Neuropharmacology, 2016, Volume: 101

    Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Antagonists; Female; GABA

2016
Developmental exposure to PCBs alters the activation of the auditory cortex in response to GABA
    Neurotoxicology, 2016, Volume: 56

    Topics: Afferent Pathways; Animals; Animals, Newborn; Auditory Cortex; Electric Stimulation; Environmental P

2016
Abolishment of serotonergic neurotransmission to cardiac vagal neurons during and after hypoxia and hypercapnia with prenatal nicotine exposure.
    Journal of neurophysiology, 2009, Volume: 101, Issue:3

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Conotoxins; Dose

2009
Deficits in development of synaptic plasticity in rat dorsal striatum following prenatal and neonatal exposure to low-dose bisphenol A.
    Neuroscience, 2009, Mar-03, Volume: 159, Issue:1

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzazepines; Benzhydryl Compounds; Co

2009
Prenatal ethanol exposure persistently impairs NMDA receptor-dependent activation of extracellular signal-regulated kinase in the mouse dentate gyrus.
    Journal of neurochemistry, 2009, Volume: 109, Issue:5

    Topics: Analysis of Variance; Animals; Butadienes; Dentate Gyrus; Dizocilpine Maleate; Embryo, Mammalian; En

2009
Early, time-dependent disturbances of hippocampal synaptic transmission and plasticity after in utero immune challenge.
    Biological psychiatry, 2011, Nov-15, Volume: 70, Issue:10

    Topics: Age Factors; Animals; Animals, Newborn; Biophysics; CA1 Region, Hippocampal; Electric Stimulation; E

2011
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