2-amino-5-phosphonovalerate has been researched along with Cognition Disorders in 9 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Locklear, MN | 1 |
| Bhamidipaty, S | 1 |
| Kritzer, MF | 1 |
| Yuen, EY | 1 |
| Wei, J | 1 |
| Liu, W | 1 |
| Zhong, P | 1 |
| Li, X | 1 |
| Yan, Z | 1 |
| Kleschevnikov, AM | 1 |
| Belichenko, PV | 1 |
| Villar, AJ | 1 |
| Epstein, CJ | 1 |
| Malenka, RC | 1 |
| Mobley, WC | 1 |
| Murphy, GG | 1 |
| Shah, V | 1 |
| Hell, JW | 1 |
| Silva, AJ | 1 |
| Lahtinen, H | 1 |
| Ylinen, A | 1 |
| Hyvönen, M | 1 |
| Sirviö, J | 1 |
| Miettinen, R | 1 |
| Riekkinen, PJ | 1 |
| Ramakers, GM | 1 |
| Urban, IJ | 1 |
| De Graan, PN | 1 |
| Di Luca, M | 1 |
| Cattabeni, F | 1 |
| Gispen, WH | 1 |
| Perez-Alcazar, M | 1 |
| Daborg, J | 1 |
| Stokowska, A | 1 |
| Wasling, P | 1 |
| Björefeldt, A | 1 |
| Kalm, M | 1 |
| Zetterberg, H | 1 |
| Carlström, KE | 1 |
| Blomgren, K | 1 |
| Ekdahl, CT | 1 |
| Hanse, E | 1 |
| Pekna, M | 1 |
| Stewart, LS | 1 |
| Wu, Y | 1 |
| Eubanks, JH | 1 |
| Han, H | 1 |
| Leschenko, Y | 1 |
| Perez Velazquez, JL | 1 |
| Cortez, MA | 1 |
| Snead, OC | 1 |
| Kobayashi, M | 1 |
| Masaki, T | 1 |
| Hori, K | 1 |
| Masuo, Y | 1 |
| Miyamoto, M | 1 |
| Tsubokawa, H | 1 |
| Noguchi, H | 1 |
| Nomura, M | 1 |
| Takamatsu, K | 1 |
9 other studies available for 2-amino-5-phosphonovalerate and Cognition Disorders
| Article | Year |
|---|---|
Local N-methyl-d-aspartate receptor antagonism in the prefrontal cortex attenuates spatial cognitive deficits induced by gonadectomy in adult male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Estradiol; Excitatory Amino Acid Antagoni | 2015 |
Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Bi | 2012 |
Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Crosses, Genetic; Dentate Gyrus; Disease | 2004 |
Investigation of age-related cognitive decline using mice as a model system: neurophysiological correlates.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Calcium; Calcium Channels, L-Type; Cognition Disorders; | 2006 |
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamate | 1993 |
The impaired long-term potentiation in the CA1 field of the hippocampus of cognitive deficient microencephalic rats is restored by D-serine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cognition Disorders; Electric Stimulation; Electrophysi | 1993 |
Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3.
Topics: Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Complement C3; Disease Models, A | 2014 |
Severity of atypical absence phenotype in GABAB transgenic mice is subunit specific.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Autoradiography; Cognition Disorder | 2009 |
Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory.
Topics: Animals; Association Learning; Avoidance Learning; Behavior, Animal; Blotting, Western; Brain; Cadmi | 2005 |