2-amino-5-phosphonovalerate has been researched along with Clostridium tetani Infection in 2 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Potassium-induced potentiation of the Schaffer collateral/commissural synapses demonstrated several features characteristic of tetanus-induced LTP: (1) population excitatory post-synaptic potential (EPSP) amplitudes were enhanced to a similar magnitude (on average 70% above baseline) which (2) lasted for more than 20 min; (3) induction was blocked by bath application of the specific N-methyl-D-aspartate (NMDA) receptor antagonist D-2-amino-5-phosphonovalerate (D-APV), and (4) was attenuated by reduction of the concentration of calcium in the extracellular medium." | 3.68 | Potassium-induced long-term potentiation in rat hippocampal slices. ( Barrionuevo, G; Fleck, MW; Palmer, AM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fleck, MW | 1 |
| Palmer, AM | 1 |
| Barrionuevo, G | 1 |
| Morozov, A | 1 |
| Muzzio, IA | 1 |
| Bourtchouladze, R | 1 |
| Van-Strien, N | 1 |
| Lapidus, K | 1 |
| Yin, D | 1 |
| Winder, DG | 1 |
| Adams, JP | 1 |
| Sweatt, JD | 1 |
| Kandel, ER | 1 |
2 other studies available for 2-amino-5-phosphonovalerate and Clostridium tetani Infection
| Article | Year |
|---|---|
Potassium-induced long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Arginine Vasopressin; Electric Stimulation; | 1992 |
Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory.
Topics: Animals; Antirheumatic Agents; Bacterial Proteins; Behavior, Animal; Blotting, Western; Colforsin; C | 2003 |