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2-amino-5-phosphonovalerate and Brain Swelling

2-amino-5-phosphonovalerate has been researched along with Brain Swelling in 6 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Research Excerpts

ExcerptRelevanceReference
"Each of these could also contribute to cerebral edema, which is the primary cause of patient mortality after stroke."1.32Brain edema induced by in vitro ischemia: causal factors and neuroprotection. ( Avshalumov, MV; MacGregor, DG; Rice, ME, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khama-Murad, AKh1
MacGregor, DG1
Avshalumov, MV1
Rice, ME1
Sauer, D2
Allegrini, PR2
Cosenti, A1
Pataki, A1
Amacker, H2
Fagg, GE2
Häntzschel, A1
Andreas, K1
Thedinga, KH1
Massieu, L1
Mrsulja, BB1
Stanimirović, D1
Mićić, DV1
Spatz, M1

Other Studies

6 other studies available for 2-amino-5-phosphonovalerate and Brain Swelling

ArticleYear
[Edema in nervous tissue studied on model of hemorrhagic stroke in vitro].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Edema; Disease Models, Animal; Excitatory Amino Acid Ant

2011
Brain edema induced by in vitro ischemia: causal factors and neuroprotection.
    Journal of neurochemistry, 2003, Volume: 85, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Antioxidants; Brain Edem

2003
Characterization of the cerebroprotective efficacy of the competitive NMDA receptor antagonist CGP40116 in a rat model of focal cerebral ischemia: an in vivo magnetic resonance imaging study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Brain; Brain Edema; Brain Ischemia; Cats

1993
Efficacy of glutamate receptor antagonists in the management of functional disorders in cytotoxic brain oedema induced by hexachlorophene.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain; Brain Edema; Dizo

1998
Evaluation of quinolinic acid induced excitotoxic neurodegeneration in rat striatum by quantitative magnetic resonance imaging in vivo.
    Journal of neuroscience methods, 1992, Volume: 42, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Edema; Choline O-Acetyltransferase; Corpus Striat

1992
Excitatory amino acid receptors, oxido-reductive processes and brain oedema following transient ischaemia in gerbils.
    Acta neurochirurgica. Supplementum, 1990, Volume: 51

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anions; Brain Edema; Female; Gerbillinae; Ischemi

1990