2-amino-5-phosphonovalerate has been researched along with Bradycardia in 6 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsieh, YC | 1 |
| Chen, RF | 1 |
| Su, CK | 1 |
| Chen, SH | 1 |
| Hsieh, JH | 1 |
| Bhatnagar, T | 1 |
| Chitravanshi, VC | 1 |
| Sapru, HN | 1 |
| Canesin, RO | 1 |
| Bonagamba, LG | 2 |
| Machado, BH | 2 |
| Frigero, M | 1 |
| N'Diaye, A | 1 |
| Sévoz-Couche, C | 1 |
| Nosjean, A | 1 |
| Hamon, M | 1 |
| Laguzzi, R | 1 |
| Hong, LZ | 1 |
| Cheng, PW | 1 |
| Cheng, WH | 1 |
| Chen, SR | 1 |
| Wang, LL | 1 |
| Tseng, CJ | 1 |
6 other studies available for 2-amino-5-phosphonovalerate and Bradycardia
| Article | Year |
|---|---|
Mediation of vagal cardioinhibitory responses by glutamatergic receptors in the caudal medulla of turtles.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bradycardia; Excitatory | 2011 |
Cardiovascular responses to microinjections of excitatory amino acids into the area postrema of the rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Intravenous; Animals; Blood Pressure; Bradycardia; Cerebra | 1999 |
Bradycardic and hypotensive responses to microinjection of L-glutamate into the lateral aspect of the commissural NTS are blocked by an NMDA receptor antagonist.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Bradycardia; Excitatory Amino Acid Antagonists | 2000 |
The gain of the baroreflex bradycardia is reduced by microinjection of NMDA receptor antagonists into the nucleus tractus solitarii of awake rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baro | 2000 |
Stimulation of 5-HT2 receptors in the nucleus tractus solitarius enhances NMDA receptor-mediated reflex-evoked bradycardiac responses in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amphetamines; Anesthesia; Animals; Blood Pressure; Bradycardia; Chemore | 2001 |
Involvement of NMDA receptors in nicotine-mediated central control of hypotensive effects.
Topics: Animals; Blood Pressure; Bradycardia; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid | 2012 |