2-amino-5-phosphonovalerate has been researched along with Bone Loss, Osteoclastic in 3 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bone sialoprotein stimulates in vitro bone resorption." | 1.30 | Glutamate receptors are expressed by bone cells and are involved in bone resorption. ( Burt-Pichat, B; Chenu, C; Delmas, PD; Raynal, C; Serre, CM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chenu, C | 2 |
| Serre, CM | 1 |
| Raynal, C | 1 |
| Burt-Pichat, B | 1 |
| Delmas, PD | 1 |
| Gray, C | 1 |
| Marie, H | 1 |
| Arora, M | 1 |
| Tanaka, K | 1 |
| Boyde, A | 1 |
| Jones, S | 1 |
| Attwell, D | 1 |
| Itzstein, C | 1 |
| Espinosa, L | 1 |
3 other studies available for 2-amino-5-phosphonovalerate and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Glutamate receptors are expressed by bone cells and are involved in bone resorption.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antibodies, Monoclonal; Bone Resorption; Dizocilpine Maleate; | 1998 |
Glutamate does not play a major role in controlling bone growth.
Topics: 2-Amino-5-phosphonovalerate; Alveolar Bone Loss; Amino Acid Transport System X-AG; Animals; Animals, | 2001 |
Absence of evidence is not evidence of absence. Redundancy blocks determination of cause and effect.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Transport System X-AG; Animals; Bone Resorption; Dizocilpine | 2001 |