2-amino-5-phosphonovalerate has been researched along with Body Weight in 14 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The behavioral changes associated with seizures induced by auditory stimulation in magnesium (Mg)-deficient rats originate in deep brain structures and secondarily project to neocortex." | 1.29 | In vivo assessment of prevention of white-noise-induced seizure in magnesium-deficient rats by N-methyl-D-aspartate receptor blockers. ( Abe, S; Akazawa, K; Chishaki, A; Goto, Y; Kato, M; Nakamura, M, 1994) |
| "Cyanoketone-treated animals showed an impaired corticosterone secretion in response to the stressor, while basal levels were maintained." | 1.29 | Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors. ( Magariños, AM; McEwen, BS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tong, Q | 1 |
| Ye, CP | 1 |
| Jones, JE | 1 |
| Elmquist, JK | 1 |
| Lowell, BB | 1 |
| Braga, MF | 1 |
| Aroniadou-Anderjaska, V | 1 |
| Manion, ST | 1 |
| Hough, CJ | 1 |
| Li, H | 1 |
| Nakamura, M | 1 |
| Abe, S | 1 |
| Goto, Y | 1 |
| Chishaki, A | 1 |
| Akazawa, K | 1 |
| Kato, M | 1 |
| Facchinetti, F | 2 |
| Ciani, E | 1 |
| Dall'Olio, R | 2 |
| Virgili, M | 2 |
| Contestabile, A | 2 |
| Fonnum, F | 1 |
| Barb, CR | 1 |
| Campbell, RM | 1 |
| Armstrong, JD | 1 |
| Cox, NM | 1 |
| Magariños, AM | 1 |
| McEwen, BS | 1 |
| Stanley, BG | 1 |
| Willett, VL | 1 |
| Donias, HW | 1 |
| Dee, MG | 1 |
| Duva, MA | 1 |
| Sparapani, M | 1 |
| Tregnago, M | 1 |
| Lucchi, R | 1 |
| Gandolfi, O | 1 |
| Moran, J | 1 |
| Alavez, S | 1 |
| Rivera-Gaxiola, M | 1 |
| Valencia, A | 1 |
| Hurtado, S | 1 |
| Konno, N | 1 |
| Tsunoda, M | 1 |
| Nakano, K | 1 |
| Liu, Y | 1 |
| Daw, NW | 1 |
| Sato, H | 1 |
| Fox, K | 1 |
| Carmichael, T | 1 |
| Gingerich, R | 1 |
| Roberto, M | 1 |
| Cruz, MT | 1 |
| Gilpin, NW | 1 |
| Sabino, V | 1 |
| Schweitzer, P | 1 |
| Bajo, M | 1 |
| Cottone, P | 1 |
| Madamba, SG | 1 |
| Stouffer, DG | 1 |
| Zorrilla, EP | 1 |
| Koob, GF | 1 |
| Siggins, GR | 1 |
| Parsons, LH | 1 |
| Clark, NC | 1 |
| Nagano, N | 1 |
| Kuenzi, FM | 1 |
| Jarolimek, W | 1 |
| Huber, I | 1 |
| Walter, D | 1 |
| Wietzorrek, G | 1 |
| Boyce, S | 1 |
| Kullmann, DM | 1 |
| Striessnig, J | 1 |
| Seabrook, GR | 1 |
| Nelson, TE | 1 |
| Ur, CL | 1 |
| Gruol, DL | 1 |
1 trial available for 2-amino-5-phosphonovalerate and Body Weight
| Article | Year |
|---|---|
Aspartate and glutamate modulation of growth hormone secretion in the pig: possible site of action.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Aspartic Acid; Body Weight; Cells, Cultured; Dose-Respo | 1996 |
13 other studies available for 2-amino-5-phosphonovalerate and Body Weight
| Article | Year |
|---|---|
Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Absorptiometry, Photon; Agouti-Re | 2008 |
Stress impairs alpha(1A) adrenoceptor-mediated noradrenergic facilitation of GABAergic transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Antagonists; Adr | 2004 |
In vivo assessment of prevention of white-noise-induced seizure in magnesium-deficient rats by N-methyl-D-aspartate receptor blockers.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Body Weight; Dizocilpine Maleate | 1994 |
Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain; Brain | 1993 |
Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atrophy; Body Weight; Corticosterone; Cyanoketone; Dendrites; | 1995 |
Lateral hypothalamic NMDA receptors and glutamate as physiological mediators of eating and weight control.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Body | 1996 |
Neuronal nitric oxide synthase is permanently decreased in the cerebellum of rats subjected to chronic neonatal blockade of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzamides; Body Weight; Cerebellum; Depress | 1998 |
Effect of NMDA antagonists on the activity of glutaminase and aspartate aminotransferase in the developing rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Aspartate Aminotransferases; Body Weight; Cell Di | 1999 |
Effect of tributyltin on the N-methyl-D-aspartate (NMDA) receptors in the mouse brain.
Topics: 2-Amino-5-phosphonovalerate; Administration, Oral; Animals; Body Weight; Cell Membrane; Cerebral Cor | 2001 |
Cortisol reduces plasticity in the kitten visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Body Weight; Cats; Dominance, Cerebral; Dose-Response R | 1991 |
Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alcoholism; Amygdala; Animals; Body Weight; Central Nervous Sy | 2010 |
Neurological phenotype and synaptic function in mice lacking the CaV1.3 alpha subunit of neuronal L-type voltage-dependent Ca2+ channels.
Topics: Animals; Behavior, Animal; Binding Sites; Body Weight; Calcium Channel Blockers; Calcium Channels; C | 2003 |
Chronic intermittent ethanol exposure enhances NMDA-receptor-mediated synaptic responses and NMDA receptor expression in hippocampal CA1 region.
Topics: Animals; Blotting, Western; Body Weight; Brain; Central Nervous System Depressants; Dose-Response Re | 2005 |