2-amino-5-phosphonovalerate has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 3 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhattacharya, S | 1 |
| Ma, Y | 1 |
| Dunn, AR | 1 |
| Bradner, JM | 1 |
| Scimemi, A | 1 |
| Miller, GW | 1 |
| Traynelis, SF | 1 |
| Wichmann, T | 1 |
| Morin, N | 1 |
| Morissette, M | 1 |
| Grégoire, L | 1 |
| Gomez-Mancilla, B | 1 |
| Gasparini, F | 1 |
| Di Paolo, T | 1 |
| López-Huerta, VG | 1 |
| Carrillo-Reid, L | 1 |
| Galarraga, E | 1 |
| Tapia, D | 1 |
| Fiordelisio, T | 1 |
| Drucker-Colin, R | 1 |
| Bargas, J | 1 |
3 other studies available for 2-amino-5-phosphonovalerate and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
NMDA receptor blockade ameliorates abnormalities of spike firing of subthalamic nucleus neurons in a parkinsonian nonhuman primate.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2-Amino-5-phosphonovalerate; Action Potentials; Animal | 2018 |
Chronic treatment with MPEP, an mGlu5 receptor antagonist, normalizes basal ganglia glutamate neurotransmission in L-DOPA-treated parkinsonian monkeys.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Basal Ganglia; Corpus Striatum; Dyskinesia, Drug- | 2013 |
The balance of striatal feedback transmission is disrupted in a model of parkinsonism.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Anesthetics, Local; Anim | 2013 |