2-amino-5-phosphonovalerate has been researched along with Anterior Choroidal Artery Infarction in 5 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Excerpt | Relevance | Reference |
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" We herein report that treatment with CS-A after 60-min middle cerebral artery occlusion dose-dependently reduced the cerebral infarction with at least a 6-h efficacious time-window, which was partially blocked by the BKCa channel blocker charybdotoxin (CTX)." | 3.78 | Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors. ( Bai, Y; Chen, L; Li, L; Qi, J; Qi, Z; Sun, K; Yang, R; Zhang, Z; Zhou, L, 2012) |
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (80.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Neumann-Haefelin, T | 1 |
Hagemann, G | 1 |
Witte, OW | 1 |
Carletti, R | 1 |
Ratti, E | 1 |
Gaviraghi, G | 1 |
Bowery, NG | 1 |
Okada, M | 1 |
Ueda, H | 1 |
Kometani, M | 1 |
Nakao, K | 1 |
Sauer, D | 1 |
Martin, P | 1 |
Allegrini, PR | 1 |
Bernasconi, R | 1 |
Amacker, H | 1 |
Fagg, GE | 1 |
Li, L | 1 |
Yang, R | 1 |
Sun, K | 1 |
Bai, Y | 1 |
Zhang, Z | 1 |
Zhou, L | 1 |
Qi, Z | 1 |
Qi, J | 1 |
Chen, L | 1 |
5 other studies available for 2-amino-5-phosphonovalerate and Anterior Choroidal Artery Infarction
Article | Year |
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Cellular correlates of neuronal hyperexcitability in the vicinity of photochemically induced cortical infarcts in rats in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cerebral Infarction; Electrophysiology; gamma | 1995 |
Comparative receptor autoradiography of ex vivo and in vitro [3H]dizocilpine binding in mouse brain after middle cerebral artery occlusion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Binding Sites; Brain; Brain Ischemia; Cerebra | 1994 |
Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid on focal cerebral ischemia in cat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cats; Cerebral Infarction; Excitatory A | 1997 |
Differing effects of alpha-difluoromethylornithine and CGP 40116 on polyamine levels and infarct volume in a rat model of focal cerebral ischaemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Ischemia; Cerebral Infarction; Eflornithine; Magn | 1992 |
Cerebroside-A provides potent neuroprotection after cerebral ischaemia through reducing glutamate release and Ca²⁺ influx of NMDA receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebr | 2012 |