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2-amino-5-phosphonovalerate and Anochlesia

2-amino-5-phosphonovalerate has been researched along with Anochlesia in 17 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Research Excerpts

ExcerptRelevanceReference
"The present study examined whether the catalepsy induced by L-NOARG (ip) can be influenced by collicular glutamatergic mechanisms and if a NO-dependent neural substrate into the IC plays a role in this immobility state."1.38L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus. ( Barbosa-Silva, R; Iacopucci, AP; Mello, RO; Melo-Thomas, L, 2012)
"Haloperidol-induced catalepsy was challenged with prior intracollicular microinjections of glutamate NMDA receptor antagonists, MK-801 (15 or 30 mmol/0."1.36Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy. ( Brandão, ML; Coimbra, NC; Ferrari, EA; Francisco, A; Maisonnette, SS; Medeiros, P; Mello, RO; Melo, LL; Santos, P, 2010)
"These findings suggest that, while the catalepsy resulting from DA receptor blockade by haloperidol originates mainly from the VM, the expression of this phenomenon depends on an intact glutamatergic transmission within the dorsorostral CP."1.29Distinct sites of dopaminergic and glutamatergic regulation of haloperidol-induced catalepsy within the rat caudate-putamen. ( Kawano, K; Miyagishi, T; Ono, T; Yoshida, Y, 1994)
"Therefore, the THC-induced catalepsy model may be useful for distinguishing between both classes of NMDA receptor antagonists."1.29Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice. ( Hasegawa, T; Kameyama, T; Kinoshita, H; Nabeshima, T; Yamamoto, I, 1994)
"The reserpine-induced catalepsy was attenuated by CGP 37849."1.29Some central effects of CGP 37849 and CGP 39551, the competitive NMDA receptor antagonists: potential antiparkinsonian activity. ( Maj, J; Rogóz, Z; Skuza, G, 1993)
"This type of 'catalepsy' is clearly different from the state which is produced by the administration of neuroleptics, e."1.29Morphine-induced catalepsy is augmented by NMDA receptor antagonists, but is partially attenuated by an AMPA receptor antagonist. ( Schmidt, WJ; Tzschentke, TM, 1996)
"The potentiation of methadone-induced catalepsy in decorticated rats was mimicked in naive rats by intrastriatal (i."1.27Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists. ( Consolo, S; Forloni, G; Ladinsky, H; Palazzi, E, 1988)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's11 (64.71)18.2507
2000's0 (0.00)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Melo, LL1
Santos, P1
Medeiros, P1
Mello, RO2
Ferrari, EA1
Brandão, ML1
Maisonnette, SS1
Francisco, A1
Coimbra, NC1
Iacopucci, AP1
Barbosa-Silva, R1
Melo-Thomas, L1
Hauber, W3
Münkle, M2
Yoshida, Y2
Ono, T2
Kawano, K1
Miyagishi, T2
Waldenmeier, MT1
Kinoshita, H1
Hasegawa, T1
Kameyama, T1
Yamamoto, I1
Nabeshima, T1
Maj, J1
Skuza, G1
Rogóz, Z1
Tzschentke, TM1
Schmidt, WJ2
Kretschmer, BD1
Zadow, B1
Volz, TL1
Volz, L1
Sagratella, S1
Scotti de Carolis, A1
Pèzzola, A1
Popoli, P1
Urbańska, E1
Ikonomidou, C1
Sieklucka, M1
Turski, WA1
Millan, MH1
Wardley-Smith, B1
Halsey, MJ1
Meldrum, BS1
Koek, W2
Kleer, E1
Mudar, PJ1
Woods, JH2
Ornstein, P1
Consolo, S1
Forloni, G1
Ladinsky, H1
Palazzi, E1
Kizu, A1
Fukushima, R1

Other Studies

17 other studies available for 2-amino-5-phosphonovalerate and Anochlesia

ArticleYear
Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy.
    Brain research, 2010, Aug-19, Volume: 1349

    Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dose-Response Relationship, Dr

2010
L-NOARG-induced catalepsy can be influenced by glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dose-Response Relationship, Drug; Drug Administrati

2012
Stimulation of adenosine A2a receptors in the rat striatum induces catalepsy that is reversed by antagonists of N-methyl-D-aspartate receptors.
    Neuroscience letters, 1995, Aug-25, Volume: 196, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Anticonvulsants; Catalepsy; Corpus Striatum; Dizoci

1995
Distinct sites of dopaminergic and glutamatergic regulation of haloperidol-induced catalepsy within the rat caudate-putamen.
    Brain research, 1994, Mar-07, Volume: 639, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Catalepsy; Caudate Nucleus; Dopamine; Glutam

1994
The AMPA receptor antagonist GYKI 52466 reverses the anti-cataleptic effects of the competitive NMDA receptor antagonist CGP 37849.
    European journal of pharmacology, 1994, May-02, Volume: 256, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Catalep

1994
Competitive NMDA antagonists enhance the catalepsy induced by delta 9-tetrahydrocannabinol in mice.
    Neuroscience letters, 1994, Jun-06, Volume: 174, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amantadine;

1994
Some central effects of CGP 37849 and CGP 39551, the competitive NMDA receptor antagonists: potential antiparkinsonian activity.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; alpha-Methyltyrosine; Animals; Antiparkinson Agents; Antipsychotic Agen

1993
Morphine-induced catalepsy is augmented by NMDA receptor antagonists, but is partially attenuated by an AMPA receptor antagonist.
    European journal of pharmacology, 1996, Jan-11, Volume: 295, Issue:2-3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Benzodiazepines; Catalepsy; Dizocilpine M

1996
The adenosine receptor antagonist theophylline induces a monoamine-dependent increase of the anticataleptic effects of NMDA receptor antagonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Dizocilpine Maleate; Dopamine; gamma-Aminobutyric A

1996
The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior.
    Journal of neural transmission. General section, 1992, Volume: 87, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Catalepsy; Cycloserine; Dizoc

1992
Behavioural and electoencephalographic interactions between haloperidol and PCP/sigma ligands in the rat.
    Psychopharmacology, 1991, Volume: 105, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal;

1991
Aminooxyacetic acid produces excitotoxic lesions in the rat striatum.
    Synapse (New York, N.Y.), 1991, Volume: 9, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminooxyacetic Acid; Animals; Behavior, Animal; Catalepsy;

1991
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
    Experimental brain research, 1989, Volume: 78, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; G

1989
Phencyclidine-like catalepsy induced by the excitatory amino acid antagonist DL-2-amino-5-phosphonovalerate.
    Behavioural brain research, 1986, Volume: 19, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Catalepsy; Columbidae; Injections, Intraventricular; Phencycli

1986
Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate.
    Life sciences, 1986, Sep-15, Volume: 39, Issue:11

    Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Catalepsy; Columbidae; Dose-R

1986
Enhancement of opioid cataleptic response by cortical frontal deafferentation or intrastriatal injection of NMDA-receptor antagonists.
    Brain research, 1988, May-24, Volume: 449, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Catalepsy; Cerebral Cortex; Cere

1988
Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy.
    European journal of pharmacology, 1991, Oct-15, Volume: 203, Issue:2

    Topics: Animals; Catalepsy; Cerebral Cortex; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates;

1991