2-amino-5-phosphonovalerate has been researched along with Anesthesia in 27 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The intra-common carotid artery injection of NMDA (4 mg/kg) induced transient expiratory apnea followed by a brief and variably occurring period of breathing at reduced tidal volume." | 7.73 | Non-vagal apnea evoked by intra-common carotid artery injection of N-methyl-D-aspartic acid (NMDA) in anesthetized rats. ( Chrapusta, SJ; Kaczyńska, K; Szereda-Przestaszewska, M, 2006) |
| " The intra-common carotid artery injection of NMDA (4 mg/kg) induced transient expiratory apnea followed by a brief and variably occurring period of breathing at reduced tidal volume." | 3.73 | Non-vagal apnea evoked by intra-common carotid artery injection of N-methyl-D-aspartic acid (NMDA) in anesthetized rats. ( Chrapusta, SJ; Kaczyńska, K; Szereda-Przestaszewska, M, 2006) |
| " At early time points, NMDA receptor and NGC activation enhance descending facilitation; as time progresses, the dose-response curve of NMDA shifts to the left and descending inhibition dominates and masks any descending facilitation." | 1.31 | The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation. ( Dubner, R; Ren, K; Terayama, R, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 11 (40.74) | 18.2507 |
| 2000's | 13 (48.15) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, SL | 1 |
| Huang, YH | 1 |
| Kao, YL | 1 |
| Chen, GD | 2 |
| Cheng, CL | 2 |
| Peng, HY | 2 |
| Liao, JM | 2 |
| Huang, PC | 3 |
| Tsai, SJ | 1 |
| Lin, TB | 4 |
| Chang, HM | 1 |
| Lee, SD | 2 |
| Lai, CH | 1 |
| Lai, CY | 1 |
| Chiu, CH | 1 |
| Tung, KC | 1 |
| Bongianni, F | 1 |
| Mutolo, D | 1 |
| Carfì, M | 1 |
| Pantaleo, T | 1 |
| Aoki, C | 1 |
| Fujisawa, S | 1 |
| Mahadomrongkul, V | 1 |
| Shah, PJ | 1 |
| Nader, K | 1 |
| Erisir, A | 1 |
| Rampin, O | 1 |
| Monnerie, R | 1 |
| Jérôme, N | 1 |
| McKenna, K | 1 |
| Maurin, Y | 1 |
| Kaczyńska, K | 2 |
| Szereda-Przestaszewska, M | 2 |
| Pokorski, M | 1 |
| Kolesnikova, E | 1 |
| Marczak, M | 1 |
| Budzińska, K | 1 |
| Tsai, MC | 1 |
| Tang, CY | 1 |
| Chang, YT | 1 |
| Pan, SF | 1 |
| Chen, MJ | 1 |
| Chrapusta, SJ | 1 |
| Morino, M | 1 |
| Maeda, M | 1 |
| Nakai, M | 1 |
| Krieger, AJ | 1 |
| Sapru, HN | 1 |
| Moghaddam, B | 1 |
| Bolinao, ML | 1 |
| Maione, S | 1 |
| Berrino, L | 1 |
| Pizzirusso, A | 1 |
| Leyva, J | 1 |
| Stella, L | 1 |
| Rossi, F | 1 |
| Kinney, GG | 1 |
| Kocsis, B | 1 |
| Vertes, RP | 1 |
| Kawakami, Y | 1 |
| Ashida, H | 1 |
| Mouroux, M | 1 |
| Féger, J | 1 |
| Roth, LR | 1 |
| Leung, LS | 1 |
| Wang, Y | 1 |
| Ramage, AG | 1 |
| Jordan, D | 1 |
| N'Diaye, A | 1 |
| Sévoz-Couche, C | 1 |
| Nosjean, A | 1 |
| Hamon, M | 1 |
| Laguzzi, R | 1 |
| Terayama, R | 1 |
| Dubner, R | 1 |
| Ren, K | 1 |
| Thiels, E | 1 |
| Weisz, DJ | 1 |
| Berger, TW | 1 |
| Maren, S | 1 |
| Baudry, M | 1 |
| Thompson, RF | 1 |
| Marco, LA | 1 |
| Joshi, RS | 1 |
| Chronister, RB | 1 |
| Charriaut-Marlangue, C | 1 |
| Aniksztejn, L | 1 |
| Roisin, MP | 1 |
| Ben-Ari, Y | 1 |
| Fazeli, MS | 1 |
| Errington, ML | 1 |
| Dolphin, AC | 1 |
| Bliss, TV | 1 |
| Tsuno, Y | 1 |
| Kashiwadani, H | 1 |
| Mori, K | 1 |
| Canning, BJ | 1 |
| Mori, N | 1 |
27 other studies available for 2-amino-5-phosphonovalerate and Anesthesia
| Article | Year |
|---|---|
Acute anal stretch inhibits NMDA-dependent pelvic-urethra reflex potentiation via spinal GABAergic inhibition in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anal Canal; An | 2008 |
TRPV1 mediates the uterine capsaicin-induced NMDA NR2B-dependent cross-organ reflex sensitization in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Capsaicin; Dose-Response Relati | 2008 |
Respiratory responses to ionotropic glutamate receptor antagonists in the ventral respiratory group of the rabbit.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Excitatory A | 2002 |
NMDA receptor blockade in intact adult cortex increases trafficking of NR2A subunits into spines, postsynaptic densities, and axon terminals.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Cerebral Cortex; Dendrites; Excitatory Amino Acid | 2003 |
Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Bicuculline; Dose-Response Rela | 2003 |
Spinal control of erection by glutamate in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Pressure; Catheterization; Dose-Response Rel | 2004 |
Carotid sinus nerve section abolishes NMDA evoked respiratory effects in anaesthetised rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Blood Pressure; Carotid Sinu | 2005 |
Neurotransmitter mechanisms in the enhancement of the hypoxic ventilatory response by antecedent hyperoxia in the anesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Dose-Response | 2005 |
Effects of selective unilateral dorsal root(s) rhizotomy on micturition reflex in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Dose-Respons | 2006 |
Non-vagal apnea evoked by intra-common carotid artery injection of N-methyl-D-aspartic acid (NMDA) in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Anesthesia; Animals; Apnea; Blood Pressure; Carot | 2006 |
Effects of microinjection of N-methyl-D-aspartic acid into the nucleus tractus solitarii on cerebral blood flow in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Blood Pressure; Cerebrovascular Circulation; Male; | 1994 |
Glutamatergic antagonists attenuate ability of dopamine uptake blockers to increase extracellular levels of dopamine: implications for tonic influence of glutamate on dopamine release.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Chloral Hydr | 1994 |
Evidence that arcaine increases the N-methyl-D-aspartate-induced cardiovascular effects into the periaqueductal gray area of anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Biguanides; Blood Pressure; Dizocilpine Maleate; D | 1994 |
Injections of excitatory amino acid antagonists into the median raphe nucleus produce hippocampal theta rhythm in the urethane-anesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Anesthesia; Animals; Anticonvulsants; Binding, Competitive | 1994 |
Long-lasting potentiation of field potentials in primary and secondary somatosensory cortex.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Anesthesia; Animals; Anticonvulsants; Cats; Electric Stimu | 1993 |
Evidence that the parafascicular projection to the subthalamic nucleus is glutamatergic.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Electric Sti | 1993 |
Difference in LTP at basal and apical dendrites of CA1 pyramidal neurons in urethane-anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Dendrites; Electric Stimulation; Hippocampus; Long | 1995 |
Presynaptic 5-HT3 receptors evoke an excitatory response in dorsal vagal preganglionic neurones in anaesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Biguanides; Cadmium; Excitatory Amino Acid Agonist | 1998 |
Stimulation of 5-HT2 receptors in the nucleus tractus solitarius enhances NMDA receptor-mediated reflex-evoked bradycardiac responses in the rat.
Topics: 2-Amino-5-phosphonovalerate; Amphetamines; Anesthesia; Animals; Blood Pressure; Bradycardia; Chemore | 2001 |
The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electric Stimulation; Excitatory Amino Acid Agonis | 2002 |
In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory site.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electric Stimulation; Evoked Potentials; Hippocamp | 1992 |
Effects of the novel NMDA receptor antagonist, CGP 39551, on field potentials and the induction and expression of LTP in the dentate gyrus in vivo.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electrophysiology; Evoked Potentials; Hippocampus; | 1992 |
Effects of MK-801, a non-competitive NMDA antagonist, on linguopharyngeal events in rats.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Ataxia; Behavior, Animal; Dizocilpine Maleate; Fem | 1991 |
Release of proteins during long-term potentiation in the hippocampus of the anaesthetized rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Electric Stimulation; Hippocamp | 1988 |
Long-term potentiation in the dentate gyrus of the anaesthetized rat is accompanied by an increase in protein efflux into push-pull cannula perfusates.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Anesthesia; Animals; Calcium; Electric Stimulation; | 1988 |
Behavioral state regulation of dendrodendritic synaptic inhibition in the olfactory bulb.
Topics: Anesthesia; Animals; Behavior, Animal; Cholinergic Antagonists; Dendrites; Electric Stimulation; Ele | 2008 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citr | 2011 |