2-amino-5-phosphonovalerate has been researched along with Amnesia in 12 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "These data imply that the dorsal hippocampal NMDA receptor mechanism(s) may modulate the effect-induced by repeated morphine administration on a challenge dose of morphine-induced amnesia." | 7.77 | Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors. ( Asadi, F; Rezayof, A; Zarrindast, MR, 2011) |
| " Such insights prompted us to investigate the influence of dorsal hippocampal (CA1) NMDA receptor agents on amnesia induced by cannabinoid CB1 receptor agonist, arachidonylcyclopropylamide (ACPA) in male mice." | 3.81 | The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task. ( Amin-Yavari, S; Ebrahimi-Ghiri, M; Nasehi, M; Torabi-Nami, M; Zarrindast, MR, 2015) |
| "These data imply that the dorsal hippocampal NMDA receptor mechanism(s) may modulate the effect-induced by repeated morphine administration on a challenge dose of morphine-induced amnesia." | 3.77 | Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors. ( Asadi, F; Rezayof, A; Zarrindast, MR, 2011) |
| "We suggest that amnesia is an active process that develops over time." | 1.62 | Protein synthesis inhibitor administration before a reminder caused recovery from amnesia induced by memory reconsolidation impairment with NMDA glutamate receptor antagonist. ( Kozyrev, SA; Nikitin, PV; Nikitin, VP; Solntseva, SV, 2021) |
| "However, amnesia was not observed in snails after simultaneous injection of protein synthesis inhibitor and NMDA glutamate receptor antagonists (MK-801 + cycloheximide or APV + anisomycin) before reminding procedure." | 1.36 | [Protein synthesis is necessary for induction of amnesia, elicited by disruption of long-term memory reconsolidation]. ( Nikitin, VP; Solntseva, SV, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nasehi, M | 1 |
| Amin-Yavari, S | 1 |
| Ebrahimi-Ghiri, M | 1 |
| Torabi-Nami, M | 1 |
| Zarrindast, MR | 4 |
| Nikitin, VP | 4 |
| Kozyrev, SA | 3 |
| Solntseva, SV | 4 |
| Ardjmand, A | 1 |
| Rezayof, A | 3 |
| Asadi, F | 1 |
| Ghiasvand, M | 1 |
| Ahmadi, S | 1 |
| Wang, SH | 1 |
| Finnie, PS | 1 |
| Hardt, O | 1 |
| Nader, K | 1 |
| Liang, KC | 1 |
| Lin, MH | 1 |
| Tyan, YM | 1 |
| Xu, X | 1 |
| Russell, T | 1 |
| Bazner, J | 1 |
| Hamilton, J | 1 |
| Belfiore, P | 1 |
| Ponzio, F | 1 |
| Biagetti, R | 1 |
| Berettera, C | 1 |
| Magnani, M | 1 |
| Pozzi, O | 1 |
| Nikitin, PV | 1 |
12 other studies available for 2-amino-5-phosphonovalerate and Amnesia
| Article | Year |
|---|---|
The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Le | 2015 |
Reconsolidation of Reminder-Induced Amnesia: Role of NMDA and AMPA Glutamate Receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Avoidance Learning; Conditioning, Classical; Electros | 2015 |
Involvement of central amygdala NMDA receptor mechanism in morphine state-dependent memory retrieval.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Avoidance Learning; Dose-Response Relations | 2011 |
Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Ani | 2011 |
Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Arachidonic Acids; Avoidance Learning; Male | 2011 |
Dorsal hippocampus is necessary for novel learning but sufficient for subsequent similar learning.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Anisomycin; Calcium Channel Blockers; Conditioning, C | 2012 |
Involvement of amygdala N-methyl-D-asparate receptors in long-term retention of an inhibitory avoidance response in rats.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Avoidance Learning; Dizocilpine Maleate; Lo | 1993 |
NMDA receptor antagonist AP5 and nitric oxide synthase inhibitor 7-NI affect different phases of learning and memory in goldfish.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Avoidance Learning; Enzyme Inhibitors; Excitatory Ami | 2001 |
Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker AP7.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Amnesia; Animals; Avoidance Learning; Corpu | 1992 |
Protein synthesis inhibitor administration before a reminder caused recovery from amnesia induced by memory reconsolidation impairment with NMDA glutamate receptor antagonist.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino A | 2021 |
Peculiarities of Participation of DNA Methyltransferases in the Mechanisms of Storage, Impairment, and Recovery of Conditioned Food Aversion Memory.
Topics: Amnesia; Animals; DNA Modification Methylases; Helix, Snails; Memory; Phthalimides; Receptors, N-Met | 2018 |
[Protein synthesis is necessary for induction of amnesia, elicited by disruption of long-term memory reconsolidation].
Topics: Amnesia; Animals; Anisomycin; Cycloheximide; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; | 2010 |