2-amino-5-phosphonovalerate has been researched along with Amnesia-Memory Loss in 12 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Excerpt | Relevance | Reference |
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"These data imply that the dorsal hippocampal NMDA receptor mechanism(s) may modulate the effect-induced by repeated morphine administration on a challenge dose of morphine-induced amnesia." | 7.77 | Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors. ( Asadi, F; Rezayof, A; Zarrindast, MR, 2011) |
" Such insights prompted us to investigate the influence of dorsal hippocampal (CA1) NMDA receptor agents on amnesia induced by cannabinoid CB1 receptor agonist, arachidonylcyclopropylamide (ACPA) in male mice." | 3.81 | The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task. ( Amin-Yavari, S; Ebrahimi-Ghiri, M; Nasehi, M; Torabi-Nami, M; Zarrindast, MR, 2015) |
"These data imply that the dorsal hippocampal NMDA receptor mechanism(s) may modulate the effect-induced by repeated morphine administration on a challenge dose of morphine-induced amnesia." | 3.77 | Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors. ( Asadi, F; Rezayof, A; Zarrindast, MR, 2011) |
"We suggest that amnesia is an active process that develops over time." | 1.62 | Protein synthesis inhibitor administration before a reminder caused recovery from amnesia induced by memory reconsolidation impairment with NMDA glutamate receptor antagonist. ( Kozyrev, SA; Nikitin, PV; Nikitin, VP; Solntseva, SV, 2021) |
"However, amnesia was not observed in snails after simultaneous injection of protein synthesis inhibitor and NMDA glutamate receptor antagonists (MK-801 + cycloheximide or APV + anisomycin) before reminding procedure." | 1.36 | [Protein synthesis is necessary for induction of amnesia, elicited by disruption of long-term memory reconsolidation]. ( Nikitin, VP; Solntseva, SV, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (16.67) | 18.2507 |
2000's | 1 (8.33) | 29.6817 |
2010's | 8 (66.67) | 24.3611 |
2020's | 1 (8.33) | 2.80 |
Authors | Studies |
---|---|
Nasehi, M | 1 |
Amin-Yavari, S | 1 |
Ebrahimi-Ghiri, M | 1 |
Torabi-Nami, M | 1 |
Zarrindast, MR | 4 |
Nikitin, VP | 4 |
Kozyrev, SA | 3 |
Solntseva, SV | 4 |
Ardjmand, A | 1 |
Rezayof, A | 3 |
Asadi, F | 1 |
Ghiasvand, M | 1 |
Ahmadi, S | 1 |
Wang, SH | 1 |
Finnie, PS | 1 |
Hardt, O | 1 |
Nader, K | 1 |
Liang, KC | 1 |
Lin, MH | 1 |
Tyan, YM | 1 |
Xu, X | 1 |
Russell, T | 1 |
Bazner, J | 1 |
Hamilton, J | 1 |
Belfiore, P | 1 |
Ponzio, F | 1 |
Biagetti, R | 1 |
Berettera, C | 1 |
Magnani, M | 1 |
Pozzi, O | 1 |
Nikitin, PV | 1 |
12 other studies available for 2-amino-5-phosphonovalerate and Amnesia-Memory Loss
Article | Year |
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The dual effect of CA1 NMDA receptor modulation on ACPA-induced amnesia in step-down passive avoidance learning task.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analysis of Variance; Animals; Arachidonic Acids; Avoidance Le | 2015 |
Reconsolidation of Reminder-Induced Amnesia: Role of NMDA and AMPA Glutamate Receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Avoidance Learning; Conditioning, Classical; Electros | 2015 |
Involvement of central amygdala NMDA receptor mechanism in morphine state-dependent memory retrieval.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Avoidance Learning; Dose-Response Relations | 2011 |
Repeated pretreatment of morphine prevents morphine-induced amnesia: A possible involvement for dorsal hippocampal NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Ani | 2011 |
Activation of cannabinoid CB1 receptors in the central amygdala impairs inhibitory avoidance memory consolidation via NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Arachidonic Acids; Avoidance Learning; Male | 2011 |
Dorsal hippocampus is necessary for novel learning but sufficient for subsequent similar learning.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Anisomycin; Calcium Channel Blockers; Conditioning, C | 2012 |
Involvement of amygdala N-methyl-D-asparate receptors in long-term retention of an inhibitory avoidance response in rats.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Amygdala; Animals; Avoidance Learning; Dizocilpine Maleate; Lo | 1993 |
NMDA receptor antagonist AP5 and nitric oxide synthase inhibitor 7-NI affect different phases of learning and memory in goldfish.
Topics: 2-Amino-5-phosphonovalerate; Amnesia; Animals; Avoidance Learning; Enzyme Inhibitors; Excitatory Ami | 2001 |
Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker AP7.
Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Amino Acids; Amnesia; Animals; Avoidance Learning; Corpu | 1992 |
Protein synthesis inhibitor administration before a reminder caused recovery from amnesia induced by memory reconsolidation impairment with NMDA glutamate receptor antagonist.
Topics: Amnesia; Animals; Avoidance Learning; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino A | 2021 |
Peculiarities of Participation of DNA Methyltransferases in the Mechanisms of Storage, Impairment, and Recovery of Conditioned Food Aversion Memory.
Topics: Amnesia; Animals; DNA Modification Methylases; Helix, Snails; Memory; Phthalimides; Receptors, N-Met | 2018 |
[Protein synthesis is necessary for induction of amnesia, elicited by disruption of long-term memory reconsolidation].
Topics: Amnesia; Animals; Anisomycin; Cycloheximide; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; | 2010 |