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2-amino-5-phosphonovalerate and Alcohol Abuse

2-amino-5-phosphonovalerate has been researched along with Alcohol Abuse in 5 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Research Excerpts

ExcerptRelevanceReference
"When nimodipine was given before the motor task learning and ethanol after the practice sessions, the tolerance to the ataxic effect of ethanol was increased."1.31Differential effects of a dihydropyridine calcium channel antagonist on the components of ethanol tolerance. ( Little, HJ; Smith, JW, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jerlhag, E1
Egecioglu, E1
Dickson, SL1
Engel, JA1
Rudolph, JG1
Walker, DW1
Iimuro, Y1
Thurman, RG1
Crews, FT1
Freund, G1
Anderson, KJ1
Smith, JW1
Little, HJ1
Roberto, M1
Cruz, MT1
Gilpin, NW1
Sabino, V1
Schweitzer, P1
Bajo, M1
Cottone, P1
Madamba, SG1
Stouffer, DG1
Zorrilla, EP1
Koob, GF1
Siggins, GR1
Parsons, LH1

Other Studies

5 other studies available for 2-amino-5-phosphonovalerate and Alcohol Abuse

ArticleYear
Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system.
    Addiction biology, 2011, Volume: 16, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Alcoholism; Animals; Benzoxazoles; Dopamine; Ghrelin; Limbic System; Ma

2011
NMDA receptor binding in adult rat brain after several chronic ethanol treatment protocols.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; Alcoholism; Animals; Binding, Competitive; Brain; Brain Mapping; Dizoci

1997
Glutamate receptors in the cingulate cortex, hippocampus, and cerebellar vermis of alcoholics.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Aged; Alcoholism; Cerebellar Cortex; Dizocilpine Maleate; Excitatory Am

1999
Differential effects of a dihydropyridine calcium channel antagonist on the components of ethanol tolerance.
    Brain research, 2000, Apr-28, Volume: 863, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Ataxia;

2000
Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.
    Biological psychiatry, 2010, May-01, Volume: 67, Issue:9

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alcoholism; Amygdala; Animals; Body Weight; Central Nervous Sy

2010