2-amino-5-phosphonovalerate has been researched along with Alcohol Abuse in 5 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When nimodipine was given before the motor task learning and ethanol after the practice sessions, the tolerance to the ataxic effect of ethanol was increased." | 1.31 | Differential effects of a dihydropyridine calcium channel antagonist on the components of ethanol tolerance. ( Little, HJ; Smith, JW, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jerlhag, E | 1 |
| Egecioglu, E | 1 |
| Dickson, SL | 1 |
| Engel, JA | 1 |
| Rudolph, JG | 1 |
| Walker, DW | 1 |
| Iimuro, Y | 1 |
| Thurman, RG | 1 |
| Crews, FT | 1 |
| Freund, G | 1 |
| Anderson, KJ | 1 |
| Smith, JW | 1 |
| Little, HJ | 1 |
| Roberto, M | 1 |
| Cruz, MT | 1 |
| Gilpin, NW | 1 |
| Sabino, V | 1 |
| Schweitzer, P | 1 |
| Bajo, M | 1 |
| Cottone, P | 1 |
| Madamba, SG | 1 |
| Stouffer, DG | 1 |
| Zorrilla, EP | 1 |
| Koob, GF | 1 |
| Siggins, GR | 1 |
| Parsons, LH | 1 |
5 other studies available for 2-amino-5-phosphonovalerate and Alcohol Abuse
| Article | Year |
|---|---|
Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system.
Topics: 2-Amino-5-phosphonovalerate; Alcoholism; Animals; Benzoxazoles; Dopamine; Ghrelin; Limbic System; Ma | 2011 |
NMDA receptor binding in adult rat brain after several chronic ethanol treatment protocols.
Topics: 2-Amino-5-phosphonovalerate; Alcoholism; Animals; Binding, Competitive; Brain; Brain Mapping; Dizoci | 1997 |
Glutamate receptors in the cingulate cortex, hippocampus, and cerebellar vermis of alcoholics.
Topics: 2-Amino-5-phosphonovalerate; Aged; Alcoholism; Cerebellar Cortex; Dizocilpine Maleate; Excitatory Am | 1999 |
Differential effects of a dihydropyridine calcium channel antagonist on the components of ethanol tolerance.
Topics: 2-Amino-5-phosphonovalerate; Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Ataxia; | 2000 |
Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alcoholism; Amygdala; Animals; Body Weight; Central Nervous Sy | 2010 |