2-amino-5-phosphonovalerate has been researched along with Acute Edematous Pancreatitis in 2 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Excerpt | Relevance | Reference |
---|---|---|
" The current study examined spinal coadministration of low doses of NMDA receptor antagonist, D-(-)-2-Amino-5-phosphonovalerate (D-APV), and mu-opioid receptor agonist, morphine sulfate (MS), in reducing visceral nociception using an acute bradykinin induced pancreatitis model in rats." | 7.72 | Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model. ( Lu, Y; Vera-Portocarrero, LP; Westlund, KN, 2003) |
" The current study examined spinal coadministration of low doses of NMDA receptor antagonist, D-(-)-2-Amino-5-phosphonovalerate (D-APV), and mu-opioid receptor agonist, morphine sulfate (MS), in reducing visceral nociception using an acute bradykinin induced pancreatitis model in rats." | 3.72 | Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model. ( Lu, Y; Vera-Portocarrero, LP; Westlund, KN, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lu, Y | 1 |
Vera-Portocarrero, LP | 1 |
Westlund, KN | 2 |
Zhang, L | 1 |
Zhang, X | 1 |
2 other studies available for 2-amino-5-phosphonovalerate and Acute Edematous Pancreatitis
Article | Year |
---|---|
Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bradykinin; Disease Models, Animal; Drug Therapy, Combination; | 2003 |
Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis.
Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; | 2004 |