Compounds > 2-amino-5-phosphonovalerate
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2-amino-5-phosphonovalerate and Acute Disease

2-amino-5-phosphonovalerate has been researched along with Acute Disease in 5 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Acute Disease: Disease having a short and relatively severe course.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nishiyama, T1
Sluka, KA1
Jordan, HH1
Willis, WD1
Westlund, KN2
de Curtis, M1
Radici, C1
Forti, M1
Shors, TJ1
Zhang, L1
Zhang, X1

Other Studies

5 other studies available for 2-amino-5-phosphonovalerate and Acute Disease

ArticleYear
Interaction between a NMDA receptor antagonist, AP-5 and an AMPA receptor antagonist, YM 872 in antinociception in the spinal cord.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Acute Disease; Analgesics; Animals; Chronic Disease; Dose-Response Rela

2008
Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on spinal release of amino acids after development of acute arthritis in rats.
    Brain research, 1994, Nov-21, Volume: 664, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acute Disease; Amino Acids; Analy

1994
Cellular mechanisms underlying spontaneous interictal spikes in an acute model of focal cortical epileptogenesis.
    Neuroscience, 1999, Volume: 88, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Acute Disease;

1999
Acute stress and re-exposure to the stressful context suppress spontaneous unit activity in the basolateral amygdala via NMDA receptor activation.
    Neuroreport, 1999, Sep-09, Volume: 10, Issue:13

    Topics: 2-Amino-5-phosphonovalerate; Acute Disease; Amygdala; Animals; Excitatory Amino Acid Antagonists; Ma

1999
Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:1

    Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors;

2004