2-amino-5-phosphonovalerate has been researched along with Acquired-Immune Deficiency Syndrome Dementia Complex in 1 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, Tat, at similar concentrations, was toxic to human fetal neurons in culture." | 1.29 | Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity. ( Brownstone, RM; Geiger, JD; Knudsen, BE; Magnuson, DS; Nath, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Magnuson, DS | 1 |
| Knudsen, BE | 1 |
| Geiger, JD | 1 |
| Brownstone, RM | 1 |
| Nath, A | 1 |
1 other study available for 2-amino-5-phosphonovalerate and Acquired-Immune Deficiency Syndrome Dementia Complex
| Article | Year |
|---|---|
Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.
Topics: 2-Amino-5-phosphonovalerate; AIDS Dementia Complex; Animals; Cells, Cultured; Cerebral Cortex; Dose- | 1995 |