2-amino-5-phosphonovalerate has been researched along with ALS - Amyotrophic Lateral Sclerosis in 3 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, I | 1 |
| Nalini, A | 1 |
| Joshi, NB | 1 |
| Joshi, PG | 1 |
| Couratier, P | 1 |
| Hugon, J | 1 |
| Sindou, P | 1 |
| Vallat, JM | 1 |
| Dumas, M | 1 |
| Mennini, T | 1 |
| Cagnotto, A | 1 |
| Carvelli, L | 1 |
| Comoletti, D | 1 |
| Manzoni, C | 1 |
| Muzio, V | 1 |
| Rizzi, M | 1 |
| Vezzani, A | 1 |
3 other studies available for 2-amino-5-phosphonovalerate and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Cerebrospinal fluid from amyotrophic lateral sclerosis patients preferentially elevates intracellular calcium and toxicity in motor neurons via AMPA/kainate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Calcium; | 2005 |
Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Amino Acids; Amyotrophic La | 1993 |
Biochemical and pharmacological evidence of a functional role of AMPA receptors in motor neuron dysfunction in mnd mice.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amyotrophic L | 1999 |