2-amino-5-iodo-6-phenyl-4-pyrimidinone and Adenocarcinoma

2-amino-5-iodo-6-phenyl-4-pyrimidinone has been researched along with Adenocarcinoma* in 1 studies

Other Studies

1 other study(ies) available for 2-amino-5-iodo-6-phenyl-4-pyrimidinone and Adenocarcinoma

Article	Year
Pyrimidinones: inducers of NK cell activity and antitumor immunity. Comparative immunology, microbiology and infectious diseases, 1986, Volume: 9, Issue:2-3 We have shown that pyrimidinone molecule, 2 amino-5-iodo-6-phenyl-4-pyrimidinone (AIPP) after regional administration, displayed both prophylactic and therapeutic effect on ascitic mammary adenocarcinoma, ACA-755. The antitumor effect was mediated by natural killer (NK) cells, since depletion of this lymphocyte population resulted in abrogation of AIPP-induced tumor resistance. This observation confirms the role of NK cells in antitumor immunity and suggests that AIPP may be therapeutically beneficial also in man. Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Cytosine; Female; Killer Cells, Natural; Mammary Neoplasms, Experimental; Mice	1986

Article

Year

Pyrimidinones: inducers of NK cell activity and antitumor immunity.

Comparative immunology, microbiology and infectious diseases, 1986, Volume: 9, Issue:2-3

We have shown that pyrimidinone molecule, 2 amino-5-iodo-6-phenyl-4-pyrimidinone (AIPP) after regional administration, displayed both prophylactic and therapeutic effect on ascitic mammary adenocarcinoma, ACA-755. The antitumor effect was mediated by natural killer (NK) cells, since depletion of this lymphocyte population resulted in abrogation of AIPP-induced tumor resistance. This observation confirms the role of NK cells in antitumor immunity and suggests that AIPP may be therapeutically beneficial also in man.

Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line; Cytosine; Female; Killer Cells, Natural; Mammary Neoplasms, Experimental; Mice

1986