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2-amino-4-phosphonobutyric acid and Epilepsy, Temporal Lobe

2-amino-4-phosphonobutyric acid has been researched along with Epilepsy, Temporal Lobe in 1 studies

2-amino-4-phosphonobutyric acid: glutamate antagonist in locust muscle; structure; do not confuse with L-AP4, which is the propionic acid version

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
"Neuropeptide Y (NPY) has been shown to depress hyperexcitable activity that has been acutely induced in the normal rat brain."1.30NPY inhibits glutamatergic excitation in the epileptic human dentate gyrus. ( Patrylo, PR; Spencer, DD; van den Pol, AN; Williamson, A, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patrylo, PR1
van den Pol, AN1
Spencer, DD1
Williamson, A1

Other Studies

1 other study available for 2-amino-4-phosphonobutyric acid and Epilepsy, Temporal Lobe

ArticleYear
NPY inhibits glutamatergic excitation in the epileptic human dentate gyrus.
    Journal of neurophysiology, 1999, Volume: 82, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Animals; Axons; Dentate Gyrus; Electric Stimulation; El

1999