Page last updated: 2024-10-22

2-amino-4-phosphonobutyric acid and Disease Models, Animal

2-amino-4-phosphonobutyric acid has been researched along with Disease Models, Animal in 17 studies

2-amino-4-phosphonobutyric acid: glutamate antagonist in locust muscle; structure; do not confuse with L-AP4, which is the propionic acid version

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Chronic neuropathic pain remains an unmet clinical problem because it is often resistant to conventional analgesics."1.35Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain. ( Chen, SR; Pan, HL; Zhang, HM, 2009)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (52.94)29.6817
2010's7 (41.18)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W2
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Zhang, HM1
Chen, SR1
Pan, HL1
Maciejak, P1
Szyndler, J1
Turzyńska, D1
Sobolewska, A1
Taracha, E1
Skórzewska, A1
Lehner, M1
Bidziński, A1
Hamed, A1
Wisłowska-Stanek, A1
Płaźnik, A1
Austin, PJ1
Betts, MJ1
Broadstock, M1
O'Neill, MJ1
Mitchell, SN1
Duty, S1
Maurer, CM1
Schönthaler, HB1
Mueller, KP1
Neuhauss, SC1
Dolan, S1
Gunn, MD1
Crossan, C1
Nolan, AM1
Nishimura, T1
Machida, S1
Kondo, M1
Terasaki, H1
Yokoyama, D1
Kurosaka, D1
Johnson, KA1
Jones, CK1
Tantawy, MN1
Bubser, M1
Marvanova, M1
Ansari, MS1
Baldwin, RM1
Conn, PJ2
Niswender, CM1
Bogenpohl, J1
Galvan, A1
Hu, X1
Wichmann, T1
Smith, Y1
Valenti, O1
Marino, MJ1
Wittmann, M1
Lis, E1
DiLella, AG1
Kinney, GG1
Zhou, F1
Hongmin, B1
Xiang, Z1
Enyu, L1
Neugebauer, V1
Ng, YF1
Chan, HH1
Chu, PH1
To, CH1
Gilger, BC1
Petters, RM1
Wong, F1
Vernon, AC1
Croucher, MJ1
Dexter, DT1
Shirato, S1
Maeda, H1
Miura, G1
Frishman, LJ1
Mills, CD1
Johnson, KM1
Hulsebosch, CE1

Other Studies

17 other studies available for 2-amino-4-phosphonobutyric acid and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain.
    Neuroscience, 2009, Jan-23, Volume: 158, Issue:2

    Topics: Aminobutyrates; Animals; Biophysical Phenomena; Disease Models, Animal; Dose-Response Relationship,

2009
The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.
    Brain research, 2009, Jul-28, Volume: 1282

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Convulsants; Disease Models, Animal; Dose-Response Re

2009
Symptomatic and neuroprotective effects following activation of nigral group III metabotropic glutamate receptors in rodent models of Parkinson's disease.
    British journal of pharmacology, 2010, Volume: 160, Issue:7

    Topics: Aminobutyrates; Animals; Aspartic Acid; Disease Models, Animal; Excitatory Amino Acid Agonists; Glut

2010
Distinct retinal deficits in a zebrafish pyruvate dehydrogenase-deficient mutant.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Sep-08, Volume: 30, Issue:36

    Topics: Aminobutyrates; Analysis of Variance; Animals; Animals, Genetically Modified; Aspartic Acid; Choline

2010
Activation of metabotropic glutamate receptor 7 in spinal cord inhibits pain and hyperalgesia in a novel formalin model in sheep.
    Behavioural pharmacology, 2011, Volume: 22, Issue:5-6

    Topics: Aminobutyrates; Animals; Behavior, Animal; Benzhydryl Compounds; Disease Models, Animal; Dose-Respon

2011
Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation.
    Investigative ophthalmology & visual science, 2011, Sep-29, Volume: 52, Issue:10

    Topics: Aminobutyrates; Animals; Animals, Genetically Modified; Disease Models, Animal; Electroretinography;

2011
The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease.
    Neuropharmacology, 2013, Volume: 66

    Topics: Aminobutyrates; Animals; Benzoates; Catalepsy; Disease Models, Animal; Dopamine; Dopamine D2 Recepto

2013
Metabotropic glutamate receptor 4 in the basal ganglia of parkinsonian monkeys: ultrastructural localization and electrophysiological effects of activation in the striatopallidal complex.
    Neuropharmacology, 2013, Volume: 66

    Topics: Action Potentials; Aminobutyrates; Anilides; Animals; Corpus Striatum; Cyclohexanecarboxylic Acids;

2013
Group III metabotropic glutamate receptor-mediated modulation of the striatopallidal synapse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Aug-06, Volume: 23, Issue:18

    Topics: Adrenergic Uptake Inhibitors; Aminobutyrates; Animals; Corpus Striatum; Disease Models, Animal; Elec

2003
Changes of mGluR4 and the effects of its specific agonist L-AP4 in a rodent model of diffuse brain injury.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2003, Volume: 10, Issue:6

    Topics: Aminobutyrates; Animals; Behavior, Animal; Brain; Brain Injuries; Cell Count; Cognition Disorders; D

2003
Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain.
    Journal of neurophysiology, 2006, Volume: 96, Issue:4

    Topics: Alanine; Aminobutyrates; Amygdala; Animals; Arthritis; Bridged Bicyclo Compounds; Disease Models, An

2006
Multifocal electroretinogram in rhodopsin P347L transgenic pigs.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:5

    Topics: Aminobutyrates; Animals; Animals, Genetically Modified; Computers, Handheld; Disease Models, Animal;

2008
Additive neuroprotection by metabotropic glutamate receptor subtype-selective ligands in a rat Parkinson's model.
    Neuroreport, 2008, Mar-05, Volume: 19, Issue:4

    Topics: Aminobutyrates; Animals; Brain; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; E

2008
Postreceptoral contributions to the light-adapted ERG of mice lacking b-waves.
    Experimental eye research, 2008, Volume: 86, Issue:6

    Topics: Adaptation, Ocular; Aging; Aminobutyrates; Animals; Disease Models, Animal; Electroretinography; Mal

2008
Role of group II and group III metabotropic glutamate receptors in spinal cord injury.
    Experimental neurology, 2002, Volume: 173, Issue:1

    Topics: Aminobutyrates; Animals; Behavior, Animal; Chronic Disease; Disease Models, Animal; Excitatory Amino

2002