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2-amino-3-phosphonopropionic acid and Optic Nerve Diseases

2-amino-3-phosphonopropionic acid has been researched along with Optic Nerve Diseases in 1 studies

2-amino-3-phosphonopropionic acid: metabotropic glutamate receptor antagonist; do not confuse AP-3 used as an abbreviation for this with enhancer-binding protein AP-3 (a trans-activator) or clathrin assembly protein AP-3
2-amino-3-phosphonopropanoic acid : A non-proteinogenc alpha-amino acid that is alanine in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group.

Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fix, AS1
Schoepp, DD1
Olney, JW1
Vestre, WA1
Griffey, KI1
Johnson, JA1
Tizzano, JP1

Other Studies

1 other study available for 2-amino-3-phosphonopropionic acid and Optic Nerve Diseases

ArticleYear
Neonatal exposure to D,L-2-amino-3-phosphonopropionate (D,L-AP3) produces lesions in the eye and optic nerve of adult rats.
    Brain research. Developmental brain research, 1993, Oct-15, Volume: 75, Issue:2

    Topics: Aging; Alanine; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Eye; Eye Diseases; Male; O

1993