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2-amino-3-phosphonopropionic acid and Nerve Degeneration

2-amino-3-phosphonopropionic acid has been researched along with Nerve Degeneration in 2 studies

2-amino-3-phosphonopropionic acid: metabotropic glutamate receptor antagonist; do not confuse AP-3 used as an abbreviation for this with enhancer-binding protein AP-3 (a trans-activator) or clathrin assembly protein AP-3
2-amino-3-phosphonopropanoic acid : A non-proteinogenc alpha-amino acid that is alanine in which one of the hydrogens of the terminal methyl group has been replaced by a dihydroxy(oxido)-lambda(5)-phosphanyl group.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maginn, M1
Caldwell, M1
Kelly, JP1
Leonard, BE1
Price, MT1
Romano, C1
Fix, AS1
Tizzano, JP1
Olney, JW1

Other Studies

2 other studies available for 2-amino-3-phosphonopropionic acid and Nerve Degeneration

ArticleYear
The effect of 2-amino-3-phosphonopropionic acid (AP-3) in the gerbil model of cerebral ischaemia.
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: Alanine; Animals; Brain Ischemia; Gerbillinae; Male; Motor Activity; Nerve Degeneration; Neurons; Re

1995
Blockade of the second messenger functions of the glutamate metabotropic receptor is associated with degenerative changes in the retina and brain of immature rodents.
    Neuropharmacology, 1995, Volume: 34, Issue:8

    Topics: Alanine; Animals; Animals, Newborn; Asparagine; Brain Diseases; Excitatory Amino Acid Antagonists; I

1995