Compounds > 2-amino-3-methylimidazo(4,5-f)quinoline
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2-amino-3-methylimidazo(4,5-f)quinoline and Precancerous Conditions

2-amino-3-methylimidazo(4,5-f)quinoline has been researched along with Precancerous Conditions in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's10 (55.56)18.2507
2000's6 (33.33)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bichler, J; Ferk, F; Filipic, M; Grasl-Kraupp, B; Haslinger, E; Huber, WW; Knasmüller, S; Misík, M; Nersesyan, A; Zegura, B1
Helma, C; Huber, W; Kassie, F; Knasmüller, S; Qin, HM; Rabot, S; Schulte-Hermann, R; Uhl, M1
Kristiansen, E; Meyer, O; Mølck, AM; Thorup, I2
Chabicovsky, M; Grasl-Kraupp, B; Kassie, F; Knasmüller, S; Kundi, M; Rabot, S; Schulte-Hermann, R; Uhl, M; Verkerk, R1
Breinholt, VM; Daneshvar, B; Dragsted, LO; Mølck, AM; Poulsen, M; Svendsen, GW; Vinggaard, AM1
Bartsch, H; Cabral, R; Hirono, I; Ito, M; Matsumoto, K; Nagao, M; Ogino, H; Sato, K; Tsuda, H1
Kristiansen, E; Meyer, O; Thorup, I1
Bailey, AC; Dashwood, RH; Hernaez, JF; Schut, HA; Taoka, CR; Xu, M1
Adamson, RH; Gomez, DE; Lindsay, CK; Sinha, CC; Thorgeirsson, UP1
Aliaga, C; Garr, K; Rivenson, A; Weisburger, JH1
Hong, JT; Kim, DJ; Lee, KK1
Fukushima, S; Morimura, K; Salim, EI; Wanibuchi, H; Yamamoto, S1
Dashwood, RH; Xu, M1
Chen, R; Dashwood, RH; Xu, M1
Alexander, J; Devanaboyina, US; Eide, TJ; Feng, Y; Fretland, AJ; Hein, DW; Paulsen, JE; Steffensen, IL1
Abu-Zeid, M; Kato, R; Murayama, N; Ozawa, S; Yamazoe, Y1
Barnes, WS; Tanaka, T; Weisburger, JH; Williams, GM1

Other Studies

18 other study(ies) available for 2-amino-3-methylimidazo(4,5-f)quinoline and Precancerous Conditions

ArticleYear
Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
    Mutation research, 2010, Sep-10, Volume: 691, Issue:1-2

    Topics: Animals; Carcinogens; Colon; Colonic Neoplasms; DNA Damage; Flavonoids; Liver; Liver Neoplasms; Male; Precancerous Conditions; Propiophenones; Quinolines; Rats; Rats, Inbred F344

2010
Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions.
    Carcinogenesis, 2002, Volume: 23, Issue:7

    Topics: Animals; Carcinogens; Colon; Colonic Neoplasms; Comet Assay; Cytochrome P-450 CYP1A2; Diet; DNA Damage; Glucuronosyltransferase; Glutathione Transferase; Lepidium; Liver; Male; Mutagenicity Tests; Plant Extracts; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

2002
IQ (2-amino-3-methylimidazo[4,5-f]quinoline)-induced aberrant crypt foci and colorectal tumour development in rats fed two different carbohydrate diets.
    IARC scientific publications, 2002, Volume: 156

    Topics: Animals; Carcinogens; Colorectal Neoplasms; Dietary Sucrose; Disease Models, Animal; Liver Neoplasms; Male; Precancerous Conditions; Quinolines; Random Allocation; Rats; Rats, Inbred F344; Skin Neoplasms; Time Factors

2002
Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen.
    Carcinogenesis, 2003, Volume: 24, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP1A2; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Vegetables

2003
Effects of dietary antioxidants and 2-amino-3-methylimidazo[4,5-f]- quinoline (IQ) on preneoplastic lesions and on oxidative damage, hormonal status, and detoxification capacity in the rat.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2003, Volume: 41, Issue:10

    Topics: Animals; Antioxidants; Biomarkers; Carotenoids; Colon; Comet Assay; Diet; Glutathione Transferase; Hormones; Immunohistochemistry; Liver; Lycopene; Male; Oxidation-Reduction; Oxidative Stress; Placenta; Precancerous Conditions; Quercetin; Quinolines; Rats; Rats, Inbred F344; Resveratrol; Stilbenes

2003
Demonstration of initiation potential of carcinogens by induction of preneoplastic glutathione S-transferase P-form-positive liver cell foci: possible in vivo assay system for environmental carcinogens.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:3

    Topics: Animals; Captan; Carcinogenicity Tests; Carcinogens, Environmental; Cyclohexenes; Diethylnitrosamine; Diethylstilbestrol; Fungicides, Industrial; Glutathione Transferase; Hexachlorocyclohexane; Liver; Liver Neoplasms; Male; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

1993
Refined carbohydrate enhancement of aberrant crypt foci (ACF) in rat colon induced by the food-borne carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
    Cancer letters, 1996, Aug-02, Volume: 105, Issue:2

    Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Colon; Colonic Neoplasms; Dietary Carbohydrates; Food, Formulated; Male; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

1996
Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-f]quinoline-induced DNA adducts and colonic aberrant crypts in the F344 rat.
    Carcinogenesis, 1996, Volume: 17, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diet; DNA Adducts; Indoles; Male; Microsomes, Liver; Mutagenicity Tests; Oxidoreductases; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Salmonella typhimurium; Tea

1996
Liver tumors and possible preneoplastic lesions, induced by a food-derived heterocyclic amine in cynomolgus monkeys; a study of histology and cytokeratin expression.
    Liver, 1996, Volume: 16, Issue:2

    Topics: Animals; Bile Ducts, Intrahepatic; Carcinogens; Carcinoma, Hepatocellular; Food; Immunohistochemistry; Keratins; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Mutagens; Neoplasm Metastasis; Neovascularization, Pathologic; Precancerous Conditions; Quinolines

1996
Tea, or tea and milk, inhibit mammary gland and colon carcinogenesis in rats.
    Cancer letters, 1997, Mar-19, Volume: 114, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Colonic Diseases; Colonic Neoplasms; Female; Fibroadenoma; Intestinal Mucosa; Male; Mammary Neoplasms, Experimental; Milk; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Tea; Time Factors

1997
Differential effects of nongenotoxic and genotoxic carcinogens on the preneoplastic lesions in the rat liver.
    Archives of pharmacal research, 1998, Volume: 21, Issue:4

    Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Cell Count; Clofibrate; Diethylnitrosamine; Glutathione Transferase; Injections, Intraperitoneal; Liver Neoplasms; Male; Mutagens; Organ Size; Phenobarbital; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

1998
Dose-dependent induction of aberrant crypt foci in the colons but no neoplastic lesions in the livers of heterozygous p53-deficient mice treated with low dose 2-amino-3-methylimidazo [4,5-f]quinoline.
    Cancer letters, 1999, Apr-26, Volume: 138, Issue:1-2

    Topics: Animals; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Genes, p53; Heterozygote; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Quinolines

1999
Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis.
    Cancer letters, 1999, Sep-01, Volume: 143, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Chlorophyllides; Colon; Colonic Neoplasms; Drug Antagonism; Imidazoles; Indoles; Linoleic Acid; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

1999
Effect of carcinogen dose fractionation, diet and source of F344 rat on the induction of colonic aberrant crypts by 2-amino-3-methylimidazo[4,5-f]quinoline.
    Carcinogenesis, 1999, Volume: 20, Issue:12

    Topics: Animals; Carcinogens; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Isoenzymes; Liver; Male; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344

1999
DNA adduct levels and intestinal lesions in congenic rapid and slow acetylator syrian hamsters admi food mutagens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).
    Pharmacology & toxicology, 2000, Volume: 86, Issue:6

    Topics: Acetylation; Adenoma; Animals; Animals, Congenic; Arylamine N-Acetyltransferase; Cricetinae; DNA Adducts; DNA, Neoplasm; Female; Food; Imidazoles; Intestinal Neoplasms; Male; Mesocricetus; Mutagens; Precancerous Conditions; Quinolines

2000
IQ (2-amino-3-methylimidazo[4,5-f]quinoline)-induced aberrant crypt foci and colorectal tumour development in rats fed two different carbohydrate diets.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2001, Volume: 10, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Colorectal Neoplasms; Dietary Sucrose; Disease Models, Animal; Food, Formulated; Liver Neoplasms; Male; Precancerous Conditions; Quinolines; Random Allocation; Rats; Rats, Inbred F344; Skin Neoplasms

2001
Decrease in the metabolic activating capacities of arylamines in livers bearing hyperplastic nodules: association with the selective changes in hepatic P-450 isozymes.
    Japanese journal of cancer research : Gann, 1990, Volume: 81, Issue:3

    Topics: Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Fluorenes; Hydroxylation; Isoenzymes; Liver Neoplasms; Male; Microsomes, Liver; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Substrate Specificity; Testosterone

1990
Multipotential carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in rats.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:7

    Topics: Animals; Carcinogens; Ear Neoplasms; Female; Mammary Neoplasms, Experimental; Mutagens; Pancreatic Neoplasms; Precancerous Conditions; Quinolines; Rats

1985