Compounds > 2-amino-3-methylimidazo(4,5-f)quinoline
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2-amino-3-methylimidazo(4,5-f)quinoline and Hepatocellular Carcinoma

2-amino-3-methylimidazo(4,5-f)quinoline has been researched along with Hepatocellular Carcinoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (58.33)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kakehashi, A; Tajiri, M; Wanibuchi, H; Wei, M; Xie, XL; Yamano, S1
Kamada, N; Kato, K; Masutani, M; Nakagama, H; Ogawa, K; Shirai, T; Sugimura, T; Suzuki, H; Tang, M1
Ito, T; Jin, M; Kashida, Y; Mitsumori, K; Moto, M; Muguruma, M; Okamura, M1
Filipic, M; Lah, TT; Plazar, J; Zegura, B1
Adamson, RH; Fujimoto, Y; Hampton, LL; Nagao, M; Snyderwine, EG; Sugimura, T; Thorgeirsson, SS1
Adamson, RH; Sugimura, T; Takayama, S; Thorgeirsson, UP1
Adamson, RH; Gomez, DE; Lindsay, CK; Sinha, CC; Thorgeirsson, UP1
Adamson, RH; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS1
Darroudi, F; Knasmüller, S; Nagao, M; Parzefall, W; Sanyal, R1
Helma, C; Knasmüller, S; Uhl, M1
Darroudi, F; Knasmüller, S; Kundi, M; Land, SJ; Parzefall, W; Sanyal, R; Schwab, CE; Wang, CY1
Falnoga, I; Fatur, T; Filipic, M; Lah, TT; Scancar, J; Tusek, M1

Other Studies

12 other study(ies) available for 2-amino-3-methylimidazo(4,5-f)quinoline and Hepatocellular Carcinoma

ArticleYear
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 125, Issue:2

    Topics: Animals; beta Catenin; Blotting, Western; Body Weight; Carcinoma, Hepatocellular; Cell Adhesion; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Response Relationship, Drug; Drinking; Eating; Hepatectomy; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Mice; Organ Size; Quinolines; Time Factors; Transforming Growth Factor beta; Wnt Proteins; Wnt Signaling Pathway

2012
Parp-1 deficiency does not enhance liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline in mice.
    Cancer letters, 2006, May-08, Volume: 236, Issue:1

    Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Incidence; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Quinolines; Stomach

2006
A 26-week carcinogenicity study of 2-amino-3-methylimidazo[4,5-f]quinoline in rasH2 mice.
    Toxicologic pathology, 2006, Volume: 34, Issue:2

    Topics: Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Disease Susceptibility; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Liver Neoplasms, Experimental; Male; Mice; Mice, Transgenic; Neoplasms; Papilloma; Quinolines; Stomach Neoplasms; Time Factors

2006
Protective effects of xanthohumol against the genotoxicity of benzo(a)pyrene (BaP), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and tert-butyl hydroperoxide (t-BOOH) in HepG2 human hepatoma cells.
    Mutation research, 2007, Aug-15, Volume: 632, Issue:1-2

    Topics: Antimutagenic Agents; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet Assay; Cytoprotection; DNA Damage; Flavonoids; Humans; Liver Neoplasms; Mutagens; Propiophenones; Quinolines; Reactive Oxygen Species; tert-Butylhydroperoxide; Tumor Cells, Cultured

2007
p53 gene mutation in hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:5

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Genes, p53; Liver Neoplasms; Macaca fascicularis; Molecular Sequence Data; Mutagens; Mutation; Polymerase Chain Reaction; Quinolines

1994
Induction of hepatocellular carcinoma in nonhuman primates by the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline.
    Environmental health perspectives, 1994, Volume: 102, Issue:2

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Food Contamination; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Male; Mutagens; Quinolines

1994
Liver tumors and possible preneoplastic lesions, induced by a food-derived heterocyclic amine in cynomolgus monkeys; a study of histology and cytokeratin expression.
    Liver, 1996, Volume: 16, Issue:2

    Topics: Animals; Bile Ducts, Intrahepatic; Carcinogens; Carcinoma, Hepatocellular; Food; Immunohistochemistry; Keratins; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Mutagens; Neoplasm Metastasis; Neovascularization, Pathologic; Precancerous Conditions; Quinolines

1996
Possible relationship between tissue distribution of DNA adducts and genotoxicity of food-derived heterocyclic amines.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Amines; Animals; Carcinoma, Hepatocellular; Cattle; Cooking; DNA Adducts; Fishes; Heterocyclic Compounds; Hot Temperature; Humans; Liver Neoplasms; Macaca fascicularis; Meat; Mutagens; Poultry; Primates; Quinolines; Quinoxalines; Tissue Distribution

1995
Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens.
    Mutagenesis, 1997, Volume: 12, Issue:4

    Topics: Acrolein; Amines; Antimutagenic Agents; Benzaldehydes; Caffeine; Carbolines; Carcinoma, Hepatocellular; Coumarins; DNA Repair; Heterocyclic Compounds; Humans; Hydrolyzable Tannins; Imidazoles; Micronucleus Tests; Mutagens; Quinolines; Tumor Cells, Cultured

1997
Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells.
    Mutation research, 1999, May-17, Volume: 441, Issue:2

    Topics: Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Survival; Dimethyl Sulfoxide; Dimethylnitrosamine; DNA; DNA Damage; Electrophoresis; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Methylnitrosourea; Microscopy, Fluorescence; Mutagenicity Tests; Mutagens; Quinolines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Trypsin; Tumor Cells, Cultured

1999
Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells.
    Mutagenesis, 1999, Volume: 14, Issue:6

    Topics: Amines; Animals; Arylamine N-Acetyltransferase; Carbolines; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Survival; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Imidazoles; Liver Neoplasms; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella; Tumor Cells, Cultured

1999
DNA damage and metallothionein synthesis in human hepatoma cells (HepG2) exposed to cadmium.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:8

    Topics: Adaptation, Physiological; Benzo(a)pyrene; Cadmium; Carcinogens; Carcinoma, Hepatocellular; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Humans; Liver; Liver Neoplasms; Metallothionein; Mutagens; Quinolines; Time Factors; Tumor Cells, Cultured

2002