2-amino-3-methylimidazo(4,5-f)quinoline has been researched along with Experimental Hepatoma in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (29.63) | 18.7374 |
| 1990's | 13 (48.15) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kakehashi, A; Tajiri, M; Wanibuchi, H; Wei, M; Xie, XL; Yamano, S | 1 |
| Chabicovsky, M; Grasl-Kraupp, B; Kassie, F; Knasmüller, S; Kundi, M; Rabot, S; Schulte-Hermann, R; Uhl, M; Verkerk, R | 1 |
| Kamada, N; Kato, K; Masutani, M; Nakagama, H; Ogawa, K; Shirai, T; Sugimura, T; Suzuki, H; Tang, M | 1 |
| Ito, T; Jin, M; Kashida, Y; Mitsumori, K; Moto, M; Muguruma, M; Okamura, M | 1 |
| Ban, H; Donehower, LA; Hirata, A; Masegi, T; Sakai, H; Takasu, S; Tatematsu, M; Tsukamoto, T; Yamamoto, M; Yanai, T | 1 |
| Adamson, RH; Sugimura, T; Takayama, S; Thorgeirsson, UP | 1 |
| Blanck, A; Gustafsson, JA; Kleman, MI; Overvik, E; Porsch-Hällström, I | 1 |
| Reddy, BS; Rivenson, A | 1 |
| Adamson, RH; Gomez, DE; Lindsay, CK; Sinha, CC; Thorgeirsson, UP | 1 |
| Adamson, RH; Dalgard, DW; Thorgeirsson, UP | 1 |
| Adamson, RH; Gomez, DE; Nagy, P; Sinha, CC; Thorgeirsson, UP | 1 |
| Davis, CD; Santoni-Rugiu, E; Snyderwine, EG; Thorgeirsson, SS | 1 |
| Fukushima, S; Morimura, K; Salim, EI; Wanibuchi, H; Yamamoto, S | 1 |
| Degawa, M; Konno, Y; Moore, MA; Nakashita, K; Sekine, K; Takasuka, N; Tsuda, H; Uehara, N | 1 |
| Al-Fageeh, M; Blum, CA; Dashwood, RH; Dixon, BM; Li, Q | 1 |
| Bucci, T; Dooley, KL; Fu, PP; Kadlubar, FF; Von Tungeln, LS | 1 |
| Adamson, RH; Dalgard, DW; Reeves, J; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP | 1 |
| Adamson, RH; Schut, HA; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP; Turesky, RJ | 1 |
| Ito, N; Ozaki, K; Takahashi, S; Tsuda, H; Yamaguchi, S | 1 |
| Ikeda, I; Kitagawa, Y; Nagao, M; Sakai, R; Sasaki, K; Shima, H; Sugimura, T | 1 |
| Ito, N; Kitagawa, Y; Nagao, M; Sakai, R; Sugimura, T; Tahira, T; Tsuda, H | 1 |
| Hayashi, K; Hirohashi, S; Ishikawa, F; Nagao, M; Ochiai, M; Sugimura, T; Takaku, F; Takayama, S; Terada, M | 1 |
| Asamoto, M; Inoue, T; Ito, N; Nagao, M; Ogiso, T; Tsuda, H | 1 |
| Nagao, M | 1 |
| Hasegawa, H; Kato, T; Ohgaki, H; Sato, S; Suenaga, M; Sugimura, T; Takayama, S | 2 |
| Hayashi, K; Ishikawa, F; Nagao, M; Ochiai, M; Sugimura, T; Takaku, F; Takayama, S | 1 |
1 review(s) available for 2-amino-3-methylimidazo(4,5-f)quinoline and Experimental Hepatoma
| Article | Year |
|---|---|
[Active oncogenes in tumors of experimental animals].
Topics: Animals; Fibrosarcoma; Imidazoles; Intestinal Neoplasms; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Oncogenes; Pyrenes; Quinolines; Rats; Skin Neoplasms; Thymus Neoplasms; Transformation, Genetic | 1986 |
26 other study(ies) available for 2-amino-3-methylimidazo(4,5-f)quinoline and Experimental Hepatoma
| Article | Year |
|---|---|
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways.
Topics: Animals; beta Catenin; Blotting, Western; Body Weight; Carcinoma, Hepatocellular; Cell Adhesion; Cell Transformation, Neoplastic; Diethylnitrosamine; Dose-Response Relationship, Drug; Drinking; Eating; Hepatectomy; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Mice; Organ Size; Quinolines; Time Factors; Transforming Growth Factor beta; Wnt Proteins; Wnt Signaling Pathway | 2012 |
Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP1A2; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Vegetables | 2003 |
Parp-1 deficiency does not enhance liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline in mice.
Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Incidence; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Quinolines; Stomach | 2006 |
A 26-week carcinogenicity study of 2-amino-3-methylimidazo[4,5-f]quinoline in rasH2 mice.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Hepatocellular; Disease Susceptibility; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Liver Neoplasms, Experimental; Male; Mice; Mice, Transgenic; Neoplasms; Papilloma; Quinolines; Stomach Neoplasms; Time Factors | 2006 |
Organ-dependent susceptibility of p53 knockout mice to 2-amino-3-methylimidazo[4,5-f]quinoline (IQ).
Topics: Animals; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Disease Susceptibility; Female; Genes, p53; Liver Neoplasms, Experimental; Male; Mice; Mice, Knockout; Mutation; Organ Specificity; Quinolines; Stomach Neoplasms; Time Factors | 2007 |
Induction of hepatocellular carcinoma in nonhuman primates by the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Food Contamination; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Male; Mutagens; Quinolines | 1994 |
The heterocyclic amines IQ and MeIQx show no promotive effect in a short-term in vivo liver carcinogenesis assay.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Diethylnitrosamine; Glutathione Transferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Quinolines; Quinoxalines; Rats; Rats, Wistar | 1993 |
Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline, a food mutagen.
Topics: Animals; Bifidobacterium; Body Weight; Carcinogens; Colonic Neoplasms; Female; Intestinal Neoplasms; Intestine, Small; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Quinolines; Rats; Rats, Inbred F344; Sex Factors | 1993 |
Liver tumors and possible preneoplastic lesions, induced by a food-derived heterocyclic amine in cynomolgus monkeys; a study of histology and cytokeratin expression.
Topics: Animals; Bile Ducts, Intrahepatic; Carcinogens; Carcinoma, Hepatocellular; Food; Immunohistochemistry; Keratins; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Mutagens; Neoplasm Metastasis; Neovascularization, Pathologic; Precancerous Conditions; Quinolines | 1996 |
Laparoscopy as a means of monitoring liver tumor induction in nonhuman primates.
Topics: Animals; Carcinogens; Equipment Design; Imidazoles; Laparoscopes; Laparoscopy; Liver Neoplasms, Experimental; Macaca mulatta; Palpation; Quinolines; Quinoxalines; Reproducibility of Results; Time Factors | 1995 |
Histopathology of IQ-induced hepatocarcinogenesis in nonhuman primates.
Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Incidence; Liver; Liver Neoplasms, Experimental; Macaca fascicularis; Macaca mulatta; Neoplasm Invasiveness; Neoplasm Metastasis; Quinolines; Time Factors | 1995 |
Hepatic tumor induction in c-myc mono-transgenic and TGF-alpha/c-myc double-transgenic mice.
Topics: Animals; Carcinogens; Diethylnitrosamine; Liver Neoplasms, Experimental; Mice; Mice, Transgenic; Phenobarbital; Proto-Oncogene Proteins c-myc; Quinolines; Transforming Growth Factor alpha | 1997 |
Dose-dependent induction of aberrant crypt foci in the colons but no neoplastic lesions in the livers of heterozygous p53-deficient mice treated with low dose 2-amino-3-methylimidazo [4,5-f]quinoline.
Topics: Animals; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Genes, p53; Heterozygote; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Quinolines | 1999 |
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Experimental; Male; Phosphodiesterase Inhibitors; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1999 |
Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
Topics: Amino Acid Sequence; Animals; Base Sequence; beta Catenin; Cytoskeletal Proteins; DNA; DNA, Complementary; Exons; Genes; Introns; Liver Neoplasms, Experimental; Male; Molecular Sequence Data; Mutation; Polymorphism, Single-Stranded Conformational; Quinolines; Rats; Rats, Inbred F344; RNA, Messenger; Sequence Analysis, DNA; Trans-Activators | 2002 |
Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse.
Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Imidazoles; Liver Neoplasms, Experimental; Male; Mice; Mutagens; Quinolines; Quinoxalines | 1992 |
Carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates: induction of tumors in three macaques.
Topics: alpha-Fetoproteins; Animals; Carcinogens; Female; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Macaca fascicularis; Male; Quinolines | 1990 |
Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.
Topics: Animals; Chromatography, High Pressure Liquid; DNA; DNA Damage; Dose-Response Relationship, Immunologic; Imidazoles; Liver Neoplasms, Experimental; Macaca fascicularis; Mutagens; Quinolines; Quinoxalines | 1990 |
Comparison of initiation potential of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in an in vivo carcinogen bioassay system.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Enzyme Induction; Galactosamine; Glutathione Transferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Mutagens; Organ Size; Phenobarbital; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1990 |
Role of protein phosphatases in malignant transformation.
Topics: Animals; Autoantigens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Enzyme Induction; Ethers, Cyclic; Fibroblasts; Gene Expression Regulation, Neoplastic; Golgi Matrix Proteins; Hyperplasia; Liver; Liver Neoplasms, Experimental; Membrane Proteins; Mice; Neoplasm Proteins; Okadaic Acid; Oncogene Proteins, Viral; Oncogenes; Phosphoprotein Phosphatases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Quinolines; Rats; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Vesicular Transport Proteins | 1989 |
Molecular cloning of rat phosphoprotein phosphatase 2A beta cDNA and increased expressions of phosphatase 2A alpha and 2A beta in rat liver tumors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cloning, Molecular; DNA; Gene Expression Regulation; Liver Neoplasms; Liver Neoplasms, Experimental; Molecular Sequence Data; Phosphoprotein Phosphatases; Protein Phosphatase 2; Quinolines; Rats; Rats, Inbred F344 | 1988 |
Activated c-raf gene in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
Topics: Animals; Base Sequence; Cell Transformation, Neoplastic; DNA Restriction Enzymes; Liver Neoplasms, Experimental; Mice; Mice, Nude; Oncogenes; Quinolines; Rats; Rats, Inbred F344; Repetitive Sequences, Nucleic Acid | 1985 |
Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion.
Topics: 2-Acetylaminofluorene; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Hepatectomy; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Mutagens; Phenobarbital; Quinolines; Rats; Rats, Inbred F344; Thyroid Neoplasms | 1988 |
Induction of hepatocellular carcinoma and highly metastatic squamous cell carcinomas in the forestomach of mice by feeding 2-amino-3,4-dimethylimidazo[4,5-f]quinoline.
Topics: Animals; Carcinoma, Squamous Cell; Female; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Mutagens; Neoplasm Metastasis; Quinolines; Sex Factors; Stomach Neoplasms | 1986 |
Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Carcinoma, Squamous Cell; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Quinolines; Quinoxalines; Rats; Rats, Inbred F344; Stomach Neoplasms | 1985 |
Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
Topics: Animals; Carcinogens; Cells, Cultured; Liver Neoplasms, Experimental; Mice; Oncogenes; Quinolines; Rats; Rats, Inbred F344; Transfection | 1985 |