2-amino-3-methylimidazo(4,5-f)quinoline has been researched along with Cancer of Colon in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (59.38) | 18.2507 |
| 2000's | 11 (34.38) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bichler, J; Ferk, F; Filipic, M; Grasl-Kraupp, B; Haslinger, E; Huber, WW; Knasmüller, S; Misík, M; Nersesyan, A; Zegura, B | 1 |
| Anderson, D; Baumgartner, A; Kurzawa-Zegota, M; Najafzadeh, M | 1 |
| Helma, C; Huber, W; Kassie, F; Knasmüller, S; Qin, HM; Rabot, S; Schulte-Hermann, R; Uhl, M | 1 |
| Fukushima, S; Makino, S; Morimura, K; Murai, T; Nomura, T; Salim, EI; Wanibuchi, H | 1 |
| Chabicovsky, M; Grasl-Kraupp, B; Kassie, F; Knasmüller, S; Kundi, M; Rabot, S; Schulte-Hermann, R; Uhl, M; Verkerk, R | 1 |
| Blum, CA; Dashwood, RH; Dashwood, WM; Li, Q; Pereira, C; Tanaka, T; Xu, M; Zhong, X | 1 |
| Hirose, M; Imazawa, T; Ishii, Y; Kanki, K; Kitamura, Y; Kuroiwa, Y; Nishikawa, A; Umemura, T | 1 |
| Hirose, M; Imazawa, T; Kanki, K; Kitamura, Y; Masegi, T; Nishikawa, A; Okazaki, K; Umemura, T | 1 |
| Armbrecht, HJ; Hsu, FF; Lakshmi, VM; Wickstra, J; Zenser, TV | 1 |
| Canzian, F; Nagao, M; Serikawa, T; Sugimura, T; Ushijima, T; Wakabayashi, K | 1 |
| Ito, N; Kakiuchi, H; Makino, H; Nagao, M; Onda, M; Sugimura, T; Ushijima, T | 1 |
| Imai, K; Ito, N; Kakiuchi, H; Nagao, M; Ochiai, M; Sugimura, T; Ushijima, T; Yachi, A | 1 |
| Reddy, BS; Rivenson, A | 1 |
| Chin, SF; Dashwood, RH; Liew, C; Pariza, MW; Schut, HA | 1 |
| Canzian, F; Imai, K; Kakiuchi, H; Nagao, M; Sugimura, T; Toyota, M; Ushijima, T; Watanabe, M | 1 |
| Kristiansen, E; Meyer, O; Thorup, I | 1 |
| Bailey, AC; Dashwood, RH; Hernaez, JF; Schut, HA; Taoka, CR; Xu, M | 1 |
| Dashwood, R; Hayashi, R; Horio, D; Luk, H | 1 |
| Fletcher, JM; Hambly, RJ; Rijken, PJ; Rowland, IR; Rumney, CJ | 1 |
| Aliaga, C; Garr, K; Rivenson, A; Weisburger, JH | 1 |
| Dashwood, R; Hasaniya, N; Hernaez, J; Xu, M; Youn, K | 1 |
| Dashwood, RH; Nagao, M; Nakagama, H; Sugimura, T; Suzui, M | 1 |
| Fukushima, S; Morimura, K; Salim, EI; Wanibuchi, H; Yamamoto, S | 1 |
| Dashwood, RH; Xu, M | 1 |
| Degawa, M; Konno, Y; Moore, MA; Nakashita, K; Sekine, K; Takasuka, N; Tsuda, H; Uehara, N | 1 |
| Fukushima, S; Makino, S; Mori, S; Morimura, K; Nomura, T; Salim, EI; Wanibuchi, H; Yamamoto, S | 1 |
| Chen, R; Dashwood, RH; Xu, M | 1 |
| Bailey, GS; Blum, CA; Dashwood, RH; Fong, AT; Horio, DT; Orner, GA; Stoner, GD; Xu, M | 1 |
| Bailey, GS; Dashwood, RH; Horio, DT; Orner, GA; Stoner, GD; Xu, M | 1 |
| Dashwood, RH; Horio, DT; Orner, GA; Xu, M | 1 |
| Cooney, RV; Custer, LJ; Dashwood, RH; Franke, AA; Tanaka, Y; Xu, M | 1 |
1 review(s) available for 2-amino-3-methylimidazo(4,5-f)quinoline and Cancer of Colon
| Article | Year |
|---|---|
IQ (2-amino-3-methylimidazo[4,5-f]quinoline).
Topics: Animals; Carcinogens; Colonic Neoplasms; Cooking; Food; Food Analysis; Humans; Neoplasms; Quinolines; Rectal Neoplasms | 1993 |
31 other study(ies) available for 2-amino-3-methylimidazo(4,5-f)quinoline and Cancer of Colon
| Article | Year |
|---|---|
Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
Topics: Animals; Carcinogens; Colon; Colonic Neoplasms; DNA Damage; Flavonoids; Liver; Liver Neoplasms; Male; Precancerous Conditions; Propiophenones; Quinolines; Rats; Rats, Inbred F344 | 2010 |
The protective effect of the flavonoids on food-mutagen-induced DNA damage in peripheral blood lymphocytes from colon cancer patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cells, Cultured; Colonic Neoplasms; DNA Damage; Dose-Response Relationship, Drug; Female; Flavonoids; Food Analysis; Humans; Imidazoles; Lymphocytes; Male; Middle Aged; Mutagens; Quercetin; Quinolines; Rutin; Young Adult | 2012 |
Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions.
Topics: Animals; Carcinogens; Colon; Colonic Neoplasms; Comet Assay; Cytochrome P-450 CYP1A2; Diet; DNA Damage; Glucuronosyltransferase; Glutathione Transferase; Lepidium; Liver; Male; Mutagenicity Tests; Plant Extracts; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 2002 |
Induction of tumors in the colon and liver of the immunodeficient (SCID) mouse by 2-amino-3-methylimidazo[4,5-f ]quinoline (IQ)-modulation by long-chain fatty acids.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Body Weight; Carcinogenicity Tests; Carcinogens; Cell Division; Colonic Neoplasms; Deoxyguanosine; Disease Models, Animal; Fatty Acids; Female; Incidence; Intestinal Mucosa; Kidney; Liver; Liver Neoplasms; Mice; Mice, SCID; Mitosis; Organ Size; Quinolines | 2002 |
Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP1A2; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Vegetables | 2003 |
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
Topics: 1,2-Dimethylhydrazine; Animals; Base Sequence; beta Catenin; Carcinogens; Codon; Colonic Neoplasms; Consensus Sequence; Cytoskeletal Proteins; DNA Mutational Analysis; Genes, APC; Genes, jun; Intestinal Neoplasms; Liver Neoplasms; Male; Polymorphism, Single Nucleotide; Quinolines; Rats; Rats, Inbred F344; Skin Neoplasms; Trans-Activators | 2003 |
Induction of colon tumors in C57BL/6J mice fed MeIQx, IQ, or PhIP followed by dextran sulfate sodium treatment.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dextran Sulfate; Diet; Drug Therapy, Combination; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Quinolines; Quinoxalines | 2005 |
Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Diethylnitrosamine; DNA Damage; Drug Interactions; Indicators and Reagents; Injections, Subcutaneous; Lipid Peroxidation; Liver Neoplasms; Lung Neoplasms; Male; Oxidative Stress; Quinolines; Rats; Rats, Inbred F344; Sodium Nitrite | 2006 |
Metabolism of a heterocyclic amine colon carcinogen in young and old rats.
Topics: Aging; Animals; beta-Naphthoflavone; Biotransformation; Carbon Radioisotopes; Carcinogens; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronides; Injections, Intraperitoneal; Intestines; Kidney; Liver; Male; Molecular Structure; Quinolines; Rats; Rats, Inbred F344; Sulfuric Acid Esters; Tandem Mass Spectrometry | 2007 |
Instability of microsatellites in rat colon tumors induced by heterocyclic amines.
Topics: Animals; Colonic Neoplasms; DNA, Neoplasm; DNA, Satellite; Imidazoles; Male; Mutation; Quinolines; Rats; Rats, Inbred F344 | 1994 |
Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole, 2-amino-3-methylimidazo[4,5-f]quinoline, or 2-amino-1-methyl-6-phenylimidazo]4,5-b]pyridine.
Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Colonic Neoplasms; Genes, ras; Imidazoles; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Quinolines; Rats; Rats, Inbred F344 | 1994 |
Rare frequency of activation of the Ki-ras gene in rat colon tumors induced by heterocyclic amines: possible alternative mechanisms of human colon carcinogenesis.
Topics: Adenocarcinoma; Amines; Animals; Base Sequence; Carcinogens; Codon; Colonic Neoplasms; Exons; Gene Expression Regulation, Neoplastic; Genes, ras; Heterocyclic Compounds; Imidazoles; Male; Molecular Sequence Data; Mutation; Quinolines; Rats; Rats, Inbred F344; Transcriptional Activation | 1993 |
Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline, a food mutagen.
Topics: Animals; Bifidobacterium; Body Weight; Carcinogens; Colonic Neoplasms; Female; Intestinal Neoplasms; Intestine, Small; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Quinolines; Rats; Rats, Inbred F344; Sex Factors | 1993 |
Protection of conjugated linoleic acids against 2-amino-3- methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms.
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Colonic Neoplasms; DNA Adducts; Enzyme Induction; Linoleic Acid; Linoleic Acids; Male; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Quinolines; Rats; Rats, Inbred F344; Substrate Specificity | 1995 |
Genetic alterations in rat colon tumors induced by heterocyclic amines.
Topics: Animals; Base Sequence; Carcinogens; Colonic Neoplasms; DNA Fingerprinting; DNA, Neoplasm; DNA, Satellite; Genes, APC; Imidazoles; Male; Molecular Sequence Data; Mutagens; Mutation; Quinolines; Rats; Rats, Inbred F344 | 1996 |
Refined carbohydrate enhancement of aberrant crypt foci (ACF) in rat colon induced by the food-borne carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
Topics: Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Colon; Colonic Neoplasms; Dietary Carbohydrates; Food, Formulated; Male; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 1996 |
Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-f]quinoline-induced DNA adducts and colonic aberrant crypts in the F344 rat.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diet; DNA Adducts; Indoles; Male; Microsomes, Liver; Mutagenicity Tests; Oxidoreductases; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Salmonella typhimurium; Tea | 1996 |
Inhibition of apoptosis in colon tumors induced in the rat by 2-amino-3-methylimidazo[4,5-f]quinoline.
Topics: Adenocarcinoma; Animals; Apoptosis; Carcinogens; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Immunoenzyme Techniques; Male; Microscopy, Fluorescence; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Quinolines; Rats; Rats, Inbred F344; Tumor Suppressor Protein p53 | 1996 |
Effects of high- and low-risk diets on gut microflora-associated biomarkers of colon cancer in human flora-associated rats.
Topics: Animals; beta-Glucosidase; Biomarkers, Tumor; Body Weight; Calcium; Carcinogens; Colonic Neoplasms; Diet; Dietary Fats; Dietary Fiber; Dietary Sucrose; Female; Glucuronidase; Humans; Intestines; Male; Quinolines; Rats; Rats, Inbred F344; Risk Factors | 1997 |
Tea, or tea and milk, inhibit mammary gland and colon carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Colonic Diseases; Colonic Neoplasms; Female; Fibroadenoma; Intestinal Mucosa; Male; Mammary Neoplasms, Experimental; Milk; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Tea; Time Factors | 1997 |
Inhibitory activity of green and black tea in a free radical-generating system using 2-amino-3-methylimidazo[4,5-f]quinoline as substrate.
Topics: Animals; Anticarcinogenic Agents; Catechin; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Kinetics; Meat; Mutagens; NADPH-Ferrihemoprotein Reductase; Quinolines; Rats; Spin Labels; Tea | 1997 |
High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat.
Topics: Animals; beta Catenin; Colonic Neoplasms; Cytoskeletal Proteins; DNA, Neoplasm; Imidazoles; Mammary Neoplasms, Experimental; Mutagens; Neoplasms, Experimental; Point Mutation; Quinolines; Rats; Rats, Inbred F344; Trans-Activators | 1998 |
Dose-dependent induction of aberrant crypt foci in the colons but no neoplastic lesions in the livers of heterozygous p53-deficient mice treated with low dose 2-amino-3-methylimidazo [4,5-f]quinoline.
Topics: Animals; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Genes, p53; Heterozygote; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Quinolines | 1999 |
Chemoprevention studies of heterocyclic amine-induced colon carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Chlorophyllides; Colon; Colonic Neoplasms; Drug Antagonism; Imidazoles; Indoles; Linoleic Acid; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 1999 |
Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
Topics: Animals; Caffeine; Carcinogens; Colonic Neoplasms; Drug Synergism; Imidazoles; Liver Neoplasms, Experimental; Male; Phosphodiesterase Inhibitors; Quinolines; Quinoxalines; Rats; Rats, Inbred F344 | 1999 |
Low-dose-dependent carcinogenic potential of 2-amino-3-methylimidazo[4,5-f]quinoline in the immunodeficient (SCID) mouse colon.
Topics: Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Kidney; Liver; Male; Mice; Mice, SCID; Organ Size; Quinolines; Severe Combined Immunodeficiency | 1999 |
Effect of carcinogen dose fractionation, diet and source of F344 rat on the induction of colonic aberrant crypts by 2-amino-3-methylimidazo[4,5-f]quinoline.
Topics: Animals; Carcinogens; Colonic Neoplasms; Cytochrome P-450 Enzyme System; Diet; Dose-Response Relationship, Drug; Isoenzymes; Liver; Male; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344 | 1999 |
beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; beta Catenin; Carcinogens; Chlorophyllides; Colonic Neoplasms; Cyclin D1; Cytoskeletal Proteins; DNA Mutational Analysis; Hypoxanthine Phosphoribosyltransferase; Indoles; Male; Mutation; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Quinolines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators | 2001 |
Post-initiation effects of chlorophyllin and indole-3-carbinol in rats given 1,2-dimethylhydrazine or 2-amino-3-methyl- imidazo.
Topics: 1,2-Dimethylhydrazine; Adenosarcoma; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Chlorophyllides; Colonic Neoplasms; Disease Models, Animal; Indoles; Liver Neoplasms; Male; Quinolines; Rats; Rats, Inbred F344 | 2001 |
Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidaz.
Topics: Administration, Oral; Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Chemoprevention; Chlorophyllides; Colonic Neoplasms; Dose-Response Relationship, Drug; Homeostasis; Male; Neoplasms, Experimental; Quinolines; Rats; Rats, Inbred F344 | 2001 |
Inhibition of colonic aberrant crypt formation by the dietary flavonoids (+)-catechin and hesperidin.
Topics: Animals; Anticarcinogenic Agents; Beverages; Carcinogens; Catechin; Cell Transformation, Neoplastic; Citrus; Colon; Colonic Neoplasms; Diet; Drug Evaluation, Preclinical; Food Analysis; Hesperidin; Intestinal Mucosa; Male; Molecular Structure; Quinolines; Rats; Rats, Inbred F344; Tea; Wine | 2002 |