Compounds > 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
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2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and Carcinoma, Hepatocellular

2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline has been researched along with Carcinoma, Hepatocellular in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haza, AI; Morales, P1
Asamoto, M; Hirose, M; Inaguma, S; Ogiso, T; Shirai, T; Suzuki, S; Takahashi, S1
Fukushima, S; Funae, Y; Kang, JS; Kinoshita, A; Kushida, M; Morimura, K; Puatanachokchai, R; Wanibuchi, H; Wei, M1
Fukushima, S; Kang, JS; Mori, S; Morimura, K; Murai, T; Totsuka, Y; Wanibuchi, H1
Hirose, M; Kushida, H; Nagao, M; Ochiai, M; Sato, H; Sugimura, T; Wakabayashi, K1
Adamson, RH; Davis, CD; Schut, HA; Snyderwine, EG; Thorgeirsson, SS1
Darroudi, F; Knasmüller, S; Kundi, M; Land, SJ; Parzefall, W; Sanyal, R; Schwab, CE; Wang, CY1
Furukawa, F; Hirose, M; Koide, A; Miyauchi, M; Mori, Y; Nishikawa, A; Okazaki, K; Son, HY1

Other Studies

8 other study(ies) available for 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline and Carcinoma, Hepatocellular

ArticleYear
Effects of (+)-catechin and (-)-epicatechin on heterocyclic amines-induced oxidative DNA damage.
    Journal of applied toxicology : JAT, 2011, Volume: 31, Issue:1

    Topics: Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Imidazoles; Oxidation-Reduction; Quinoxalines

2011
Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis in rats by fenbendazole--a CYP1A2 inducer.
    Cancer letters, 2002, Nov-08, Volume: 185, Issue:1

    Topics: Animals; Antinematodal Agents; Arylamine N-Acetyltransferase; Blotting, Western; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A2; DNA Primers; Drug Combinations; Drug Synergism; Enzyme Induction; Fenbendazole; Glutathione Transferase; Immunoenzyme Techniques; Liver; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Quinoxalines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction

2002
Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol: evidence for a threshold.
    Cancer science, 2005, Volume: 96, Issue:11

    Topics: Adenoma; Administration, Oral; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Cytochrome P-450 CYP2E1; DNA Damage; Dose-Response Relationship, Drug; Enzyme Induction; Ethanol; Liver Neoplasms; Male; Quinoxalines; Rats; Rats, Inbred F344; RNA, Messenger

2005
Evidence of a threshold-effect for 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline liver carcinogenicity in F344/DuCrj rats.
    Toxicologic pathology, 2008, Volume: 36, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenoma, Liver Cell; Administration, Oral; Animal Feed; Animals; Carcinogens; Carcinoma, Hepatocellular; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Glutathione Transferase; Liver; Liver Neoplasms; Longevity; Male; No-Observed-Adverse-Effect Level; Precancerous Conditions; Quinoxalines; Rats; Rats, Inbred F344

2008
Formation and removal of DNA adducts in the liver of rats chronically fed the food-borne carcinogen, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:6

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma, Hepatocellular; DNA Adducts; Glutathione Transferase; Liver; Male; Quinoxalines; Rats; Rats, Inbred F344; Time Factors

1995
Possible relationship between tissue distribution of DNA adducts and genotoxicity of food-derived heterocyclic amines.
    Princess Takamatsu symposia, 1995, Volume: 23

    Topics: Amines; Animals; Carcinoma, Hepatocellular; Cattle; Cooking; DNA Adducts; Fishes; Heterocyclic Compounds; Hot Temperature; Humans; Liver Neoplasms; Macaca fascicularis; Meat; Mutagens; Poultry; Primates; Quinolines; Quinoxalines; Tissue Distribution

1995
Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells.
    Mutagenesis, 1999, Volume: 14, Issue:6

    Topics: Amines; Animals; Arylamine N-Acetyltransferase; Carbolines; Carcinogens; Carcinoma, Hepatocellular; Cell Line; Cell Survival; CHO Cells; Cricetinae; Heterocyclic Compounds; Humans; Imidazoles; Liver Neoplasms; Mutagenicity Tests; Mutagens; Quinolines; Quinoxalines; Rats; Salmonella; Tumor Cells, Cultured

1999
Enhancement by cigarette smoke exposure of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis in close association with elevation of hepatic CYP1A2.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:1

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; Colon; Colonic Neoplasms; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronosyltransferase; Glutathione Transferase; Immunoblotting; Liver; Liver Neoplasms, Experimental; Male; Mutagens; Organ Size; Quinoxalines; Rats; Rats, Inbred F344; Smoking

2002