2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Obesity in 2 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity is associated with an increased risk of cancer." | 1.43 | Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc. ( Chi, E; Kuo, Y; Liu, A; Wang, H; Yang, CS; Yang, X; Zhang, L, 2016) |
| "Obesity is highly associated with colon cancer development." | 1.40 | AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats. ( Fukuda, H; Hippo, Y; Igarashi, M; Nakagama, H; Ochiai, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Igarashi, M | 1 |
| Hippo, Y | 1 |
| Ochiai, M | 1 |
| Fukuda, H | 1 |
| Nakagama, H | 1 |
| Wang, H | 1 |
| Liu, A | 1 |
| Kuo, Y | 1 |
| Chi, E | 1 |
| Yang, X | 1 |
| Zhang, L | 1 |
| Yang, CS | 1 |
2 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Obesity
| Article | Year |
|---|---|
AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Carcinogenesis; Carcinogens; Cell Line; Colon; Colonic Neop | 2014 |
Obesity promotes PhIP-induced small intestinal carcinogenesis in hCYP1A-db/db mice: involvement of mutations and DNA hypermethylation of Apc.
Topics: Adenomatous Polyposis Coli Protein; Animals; beta Catenin; Carcinogenesis; Cytochrome P-450 CYP1A1; | 2016 |