Compounds > 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
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2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Neoplasm Metastasis

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Neoplasm Metastasis in 2 studies

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Treatment of the mammary cancer cell lines MCF-7 and T47D with PhIP induces cells to digest and migrate through a reconstituted basement membrane."1.37The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells. ( Gooderham, NJ; Lauber, SN, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeh, IJ1
Chen, SC1
Yen, MC1
Wu, YH1
Hung, CH1
Kuo, PL1
Lauber, SN1
Gooderham, NJ1

Other Studies

2 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Neoplasm Metastasis

ArticleYear
6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential.
    Nutrients, 2019, Sep-28, Volume: 11, Issue:10

    Topics: Carcinoma, Renal Cell; Catechols; Cell Line, Tumor; Humans; Imidazoles; Kidney Neoplasms; Neoplasm M

2019
The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells.
    Toxicology, 2011, Jan-11, Volume: 279, Issue:1-3

    Topics: Basement Membrane; Breast Neoplasms; Carcinogens; Cathepsin D; Cell Line, Tumor; Cell Movement; Cook

2011