2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Metastase in 2 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of the mammary cancer cell lines MCF-7 and T47D with PhIP induces cells to digest and migrate through a reconstituted basement membrane." | 1.37 | The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells. ( Gooderham, NJ; Lauber, SN, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, IJ | 1 |
| Chen, SC | 1 |
| Yen, MC | 1 |
| Wu, YH | 1 |
| Hung, CH | 1 |
| Kuo, PL | 1 |
| Lauber, SN | 1 |
| Gooderham, NJ | 1 |
2 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Metastase
| Article | Year |
|---|---|
6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential.
Topics: Carcinoma, Renal Cell; Catechols; Cell Line, Tumor; Humans; Imidazoles; Kidney Neoplasms; Neoplasm M | 2019 |
The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells.
Topics: Basement Membrane; Breast Neoplasms; Carcinogens; Cathepsin D; Cell Line, Tumor; Cell Movement; Cook | 2011 |