2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Intraepithelial Prostatic Neoplasia in 5 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
Excerpt | Relevance | Reference |
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"To develop a relevant mouse model for prostate cancer prevention research, we administered a dietary carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), to CYP1A-humanized mice." | 1.38 | Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice. ( Bosland, MC; Cheung, C; Li, G; Liu, AB; Reuhl, KR; Wang, H; Yang, CS, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chen, JX | 1 |
Li, G | 2 |
Wang, H | 2 |
Liu, A | 1 |
Lee, MJ | 1 |
Reuhl, K | 1 |
Suh, N | 1 |
Bosland, MC | 2 |
Yang, CS | 2 |
Liu, AB | 1 |
Cheung, C | 1 |
Reuhl, KR | 1 |
Cho, YM | 2 |
Takahashi, S | 2 |
Asamoto, M | 1 |
Suzuki, S | 2 |
Inaguma, S | 2 |
Hokaiwado, N | 1 |
Shirai, T | 2 |
Ohnishi, H | 1 |
Borowsky, AD | 1 |
Dingley, KH | 1 |
Ubick, E | 1 |
Turteltaub, KW | 1 |
Cardiff, RD | 1 |
Devere-White, R | 1 |
5 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Intraepithelial Prostatic Neoplasia
Article | Year |
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Dietary tocopherols inhibit PhIP-induced prostate carcinogenesis in CYP1A-humanized mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Cyclooxygenase 2; Cytochrome P-450 CY | 2016 |
Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.
Topics: Animals; Cadherins; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A2; Diet, Hig | 2012 |
Age-dependent histopathological findings in the prostate of probasin/SV40 T antigen transgenic rats: lack of influence of carcinogen or testosterone treatment.
Topics: Adenocarcinoma; Age Factors; Aminobiphenyl Compounds; Androgen Antagonists; Androgen-Binding Protein | 2003 |
High susceptibility of the ACI and spontaneously hypertensive rat (SHR) strains to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) prostate carcinogenesis.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Disease Progression; Disease S | 2003 |
Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model.
Topics: Animals; Atrophy; Carcinogens; Cell Proliferation; Disease Models, Animal; Glutathione Transferase; | 2006 |