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2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Hyperplasia

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Hyperplasia in 4 studies

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagiwara, A2
Miyashita, K1
Nakanishi, T1
Sano, M1
Tamano, S2
Kadota, T1
Koda, T2
Nakamura, M2
Imaida, K2
Ito, N2
Shirai, T2
Yoshino, H1
Ichihara, T1
Kawabe, M1
Aoki, H1
Kühnel, D1
Taugner, F1
Scholtka, B1
Steinberg, P1
Sliva, D1
Loganathan, J1
Jiang, J1
Jedinak, A1
Lamb, JG1
Terry, C1
Baldridge, LA1
Adamec, J1
Sandusky, GE1
Dudhgaonkar, S1

Other Studies

4 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Hyperplasia

ArticleYear
Pronounced inhibition by a natural anthocyanin, purple corn color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in male F344 rats pretreated with 1,2-dimethylhydrazine.
    Cancer letters, 2001, Sep-28, Volume: 171, Issue:1

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenocarcinoma, Mucinous; Adenoma; Administration, Oral; Anim

2001
Prevention by natural food anthocyanins, purple sweet potato color and red cabbage color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in rats initiated with 1,2-dimethylhydrazine.
    The Journal of toxicological sciences, 2002, Volume: 27, Issue:1

    Topics: 1,2-Dimethylhydrazine; Adenoma; Administration, Oral; Animals; Anthocyanins; Anticarcinogenic Agents

2002
Inflammation does not precede or accompany the induction of preneoplastic lesions in the colon of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-fed rats.
    Archives of toxicology, 2009, Volume: 83, Issue:8

    Topics: Aminopyridines; Animals; Carcinogens; Colitis; Colon; Colonic Neoplasms; Hyperplasia; Imidazoles; Ma

2009
Mushroom Ganoderma lucidum prevents colitis-associated carcinogenesis in mice.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Apoptosis; Carcinogens; Cell Proliferation; Cell

2012