2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Experimental Neoplasms in 16 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 12 (75.00) | 18.2507 |
2000's | 2 (12.50) | 29.6817 |
2010's | 2 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Williamson, R | 1 |
Kashiwabara, S | 1 |
Kashimoto, N | 1 |
Uesaka, T | 1 |
Wakabayashi, K | 3 |
Kamiya, K | 1 |
Watanabe, H | 1 |
Hasegawa, R | 3 |
Sano, M | 2 |
Tamano, S | 4 |
Imaida, K | 3 |
Shirai, T | 4 |
Nagao, M | 4 |
Sugimura, T | 6 |
Ito, N | 4 |
Rumney, CJ | 1 |
Rowland, IR | 1 |
Coutts, TM | 1 |
Randerath, K | 1 |
Reddy, R | 1 |
Shah, AB | 1 |
Ellul, A | 1 |
O'Neill, IK | 1 |
Von Tungeln, LS | 1 |
Bucci, TJ | 1 |
Hart, RW | 1 |
Kadlubar, FF | 2 |
Fu, PP | 1 |
Ushijima, T | 2 |
Makino, H | 1 |
Kakiuchi, H | 1 |
Inoue, R | 1 |
Takahashi, S | 2 |
Hirose, M | 4 |
Futakuchi, M | 1 |
Matsumoto, K | 1 |
Kristiansen, E | 1 |
Okonogi, H | 1 |
Zhang, XB | 1 |
Heddle, JA | 1 |
Suzuki, T | 1 |
Sofuni, T | 1 |
Felton, JS | 1 |
Tucker, JD | 1 |
Hagiwara, A | 1 |
Takahashi, M | 2 |
Totsuka, Y | 1 |
Masuda, M | 1 |
Fukuda, K | 1 |
Oguri, A | 1 |
Yazawa, K | 1 |
Dashwood, RH | 1 |
Suzui, M | 1 |
Nakagama, H | 1 |
Kimoto, N | 1 |
Ikeda, Y | 1 |
Sakakibara, M | 1 |
Tada, M | 1 |
Miyauchi, M | 1 |
Nishikawa, A | 1 |
Furukawa, F | 1 |
Kasahara, K | 1 |
Nakamura, H | 1 |
Schut, HA | 1 |
Yao, R | 1 |
Sliva, D | 1 |
Loganathan, J | 1 |
Jiang, J | 1 |
Jedinak, A | 1 |
Lamb, JG | 1 |
Terry, C | 1 |
Baldridge, LA | 1 |
Adamec, J | 1 |
Sandusky, GE | 1 |
Dudhgaonkar, S | 1 |
16 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Experimental Neoplasms
Article | Year |
---|---|
Scientists complete miRNA profiling of carcinogen-induced and spinach-fed colon tumors.
Topics: Animals; Carcinogens; Colonic Neoplasms; Gene Expression Profiling; Humans; Imidazoles; MicroRNAs; N | 2012 |
Tumor induction by azoxymethane (AOM) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in F344 rat gastric mucosa featuring intestinal metaplasia caused by X-irradiation.
Topics: Animals; Azoxymethane; Body Weight; Carcinogens; Carcinoma, Signet Ring Cell; Cytoplasm; Gastric Muc | 2005 |
Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats.
Topics: Adenocarcinoma; Animals; Carcinogenicity Tests; Carcinogens; Colonic Neoplasms; Dose-Response Relati | 1993 |
Effects of risk-associated human dietary macrocomponents on processes related to carcinogenesis in human-flora-associated (HFA) rats.
Topics: Animals; Biotransformation; Cecum; Cocarcinogenesis; Cross-Linking Reagents; Dietary Fats; Dietary F | 1993 |
Inhibitory effect of caloric restriction on tumorigenicity induced by 4-aminobiphenyl and 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) in the CD1 newborn mouse bioassay.
Topics: Aminobiphenyl Compounds; Animals; Animals, Newborn; Carcinogens; Diet, Reducing; Energy Intake; Imid | 1996 |
Genetic alterations in HCA-induced tumors.
Topics: Animals; Carcinogens; Colonic Neoplasms; Diet; Female; Food; Genes, p53; Genes, ras; Humans; Imidazo | 1995 |
The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods.
Topics: Animals; Carcinogens; Imidazoles; Male; Neoplasms, Experimental; Prostate; Prostatic Hyperplasia; Pr | 1997 |
The role of aberrant crypt foci induced by the two heterocyclic amines 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenyl-imidazo[4,5-b]pyridine (PhIP) in the development of colon cancer in mice.
Topics: Animals; Carcinogens; Colon; Colonic Neoplasms; Female; Imidazoles; Mice; Mice, Inbred C57BL; Neopla | 1996 |
Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents.
Topics: Animals; Bacterial Proteins; Carbolines; Cell Division; Escherichia coli Proteins; Female; Genes, AP | 1997 |
Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
Topics: Adenocarcinoma; Animals; Carcinogens; Chlorophyllides; Colonic Neoplasms; Dose-Response Relationship | 1997 |
Reduction in formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced aberrant crypt foci in the rat colon by docosahexaenoic acid (DHA).
Topics: Animals; Carcinogens; Colon; Colonic Neoplasms; DNA Adducts; Docosahexaenoic Acids; Imidazoles; Male | 1997 |
High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat.
Topics: Animals; beta Catenin; Colonic Neoplasms; Cytoskeletal Proteins; DNA, Neoplasm; Imidazoles; Mammary | 1998 |
Immunohistochemical demonstration of carcinogen-DNA adducts in tissues of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): detection in paraffin-embedded sections and tissue distribution.
Topics: Administration, Oral; Animals; Carcinogens; Colon; Cross Reactions; DNA Adducts; Enzyme-Linked Immun | 1998 |
Carcinogenic risk assessment of MeIQx and PhIP in a newborn mouse two-stage tumorigenesis assay.
Topics: Animals; Animals, Newborn; Biological Assay; Carcinogens; Imidazoles; Mice; Neoplasms, Experimental; | 1999 |
Tea as a potential chemopreventive agent in PhIP carcinogenesis: effects of green tea and black tea on PhIP-DNA adduct formation in female F-344 rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; DNA Adducts; Female; Imidazoles; Intestinal Mucosa; K | 2000 |
Mushroom Ganoderma lucidum prevents colitis-associated carcinogenesis in mice.
Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Apoptosis; Carcinogens; Cell Proliferation; Cell | 2012 |