2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Disease Exacerbation in 4 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The PhIP-induced colon cancer model in rats, thus contributes as a relevant tool to elucidate genetic factors responsible for susceptibility to colon carcinogenesis in human." | 2.41 | A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP. ( Fujiwara, K; Nagao, M; Nakagama, H; Ochiai, M; Sugimura, T; Tajima, R; Ubagai, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Syeda, T | 1 |
| Foguth, RM | 1 |
| Llewellyn, E | 1 |
| Cannon, JR | 1 |
| Nakagama, H | 1 |
| Ochiai, M | 1 |
| Ubagai, T | 1 |
| Tajima, R | 1 |
| Fujiwara, K | 1 |
| Sugimura, T | 1 |
| Nagao, M | 1 |
| Cho, YM | 2 |
| Takahashi, S | 2 |
| Asamoto, M | 1 |
| Suzuki, S | 2 |
| Inaguma, S | 2 |
| Hokaiwado, N | 1 |
| Shirai, T | 2 |
| Ohnishi, H | 1 |
1 review available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Disease Exacerbation
| Article | Year |
|---|---|
A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP.
Topics: Animals; Carcinogens; Chromosomes; Colonic Neoplasms; Disease Models, Animal; Disease Progression; G | 2002 |
3 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Disease Exacerbation
| Article | Year |
|---|---|
PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein | 2020 |
Age-dependent histopathological findings in the prostate of probasin/SV40 T antigen transgenic rats: lack of influence of carcinogen or testosterone treatment.
Topics: Adenocarcinoma; Age Factors; Aminobiphenyl Compounds; Androgen Antagonists; Androgen-Binding Protein | 2003 |
High susceptibility of the ACI and spontaneously hypertensive rat (SHR) strains to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) prostate carcinogenesis.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Disease Progression; Disease S | 2003 |