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2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Diathesis
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Diathesis in 6 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|
| "These associations may be modified by genetic susceptibility to RCC." | 1.43 | Gene-environment interaction of genome-wide association study-identified susceptibility loci and meat-cooking mutagens in the etiology of renal cell carcinoma. ( Daniel, CR; Karam, JA; Matin, SF; Melkonian, SC; Tannir, NM; Wood, CG; Wu, X; Ye, Y, 2016) |
| "Obesity is highly associated with colon cancer development." | 1.40 | AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats. ( Fukuda, H; Hippo, Y; Igarashi, M; Nakagama, H; Ochiai, M, 2014) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|
| Igarashi, M | 1 |
| Hippo, Y | 1 |
| Ochiai, M | 1 |
| Fukuda, H | 1 |
| Nakagama, H | 2 |
| Melkonian, SC | 1 |
| Daniel, CR | 1 |
| Ye, Y | 1 |
| Tannir, NM | 1 |
| Karam, JA | 1 |
| Matin, SF | 1 |
| Wood, CG | 1 |
| Wu, X | 1 |
| Inaguma, S | 1 |
| Takahashi, S | 1 |
| Ohnishi, H | 1 |
| Suzuki, S | 1 |
| Cho, YM | 1 |
| Shirai, T | 1 |
| Shan, L | 1 |
| Yu, M | 1 |
| Schut, HA | 1 |
| Snyderwine, EG | 1 |
| Nakanishi, M | 1 |
| Tazawa, H | 1 |
| Tsuchiya, N | 1 |
| Sugimura, T | 1 |
| Tanaka, T | 1 |
| Dass, SB | 1 |
| Hammons, GJ | 1 |
| Bucci, TJ | 1 |
| Heflich, RH | 1 |
| Casciano, DA | 1 |
Other Studies
6 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Diathesis
| Article | Year |
|---|
AKT is critically involved in cooperation between obesity and the dietary carcinogen amino-1-methyl-6-phenylimidazo [4,5-b] (PhIP) toward colon carcinogenesis in rats.Biochemical and biophysical research communications, 2014, Jan-17, Volume: 443, Issue:3
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Carcinogenesis; Carcinogens; Cell Line; Colon; Colonic Neop | 2014 |
Gene-environment interaction of genome-wide association study-identified susceptibility loci and meat-cooking mutagens in the etiology of renal cell carcinoma.Cancer, 2016, Jan-01, Volume: 122, Issue:1
Topics: Carcinoma, Renal Cell; Case-Control Studies; Disease Susceptibility; Female; Gene-Environment Intera | 2016 |
High susceptibility of the ACI and spontaneously hypertensive rat (SHR) strains to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) prostate carcinogenesis.Cancer science, 2003, Volume: 94, Issue:11
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Disease Progression; Disease S | 2003 |
Susceptibility of rats to mammary gland carcinogenesis by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) varies with age and is associated with the induction of differential gene expression.The American journal of pathology, 2004, Volume: 165, Issue:1
Topics: Aging; Animals; Carcinogens; Cell Differentiation; Cell Division; Cluster Analysis; Disease Suscepti | 2004 |
Mouse strain differences in inflammatory responses of colonic mucosa induced by dextran sulfate sodium cause differential susceptibility to PhIP-induced large bowel carcinogenesis.Cancer science, 2007, Volume: 98, Issue:8
Topics: Adenocarcinoma; Animals; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Colitis; Colon; Colon | 2007 |
Susceptibility of C57BL/6 mice to tumorigenicity induced by dimethylnitrosamine and 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine in the neonatal bioassay.Cancer letters, 1998, Feb-13, Volume: 124, Issue:1
Topics: Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cytochrome P-450 CYP2E1; Dimethylnitr | 1998 |