2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Colorectal Neoplasms, Hereditary Nonpolyposis

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Colorectal Neoplasms, Hereditary Nonpolyposis in 1 studies

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.

Colorectal Neoplasms, Hereditary Nonpolyposis: A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.

Research

Studies (1)

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Other Studies

1 other study available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Colorectal Neoplasms, Hereditary Nonpolyposis