2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Chromosome-Defective Micronuclei in 4 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We especially looked for any deviation from linearity of the dose-response curves." | 1.33 | A comparison of genotoxicity between three common heterocyclic amines and acrylamide. ( Abramsson-Zetterberg, L; Durling, LJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akhtar, S | 1 |
| Najafzadeh, M | 1 |
| Isreb, M | 1 |
| Newton, L | 1 |
| Gopalan, RC | 1 |
| Anderson, D | 1 |
| Durling, LJ | 1 |
| Abramsson-Zetterberg, L | 2 |
| Husøy, T | 1 |
| Ølstørn, HB | 1 |
| Paulsen, JE | 1 |
| Alexander, J | 1 |
| Hewitt, R | 1 |
| Forero, A | 1 |
| Luncsford, PJ | 1 |
| Martin, FL | 1 |
4 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Chromosome-Defective Micronuclei
| Article | Year |
|---|---|
Ex vivo/in vitro protective effect of myricetin bulk and nano-forms on PhIP-induced DNA damage in lymphocytes from healthy individuals and pre-cancerous MGUS patients.
Topics: Adult; Aged; Aged, 80 and over; Antimutagenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Pr | 2020 |
A comparison of genotoxicity between three common heterocyclic amines and acrylamide.
Topics: Acrylamide; Animals; Dose-Response Relationship, Drug; Erythrocytes; Heterocyclic Compounds; Imidazo | 2005 |
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
Topics: Acrylamide; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Colchicine; Cyt | 2005 |
Enhanced micronucleus formation and modulation of BCL-2:BAX in MCF-7 cells after exposure to binary mixtures.
Topics: bcl-2-Associated X Protein; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Cyclin-Dependent Kin | 2007 |