2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Cholestasis in 1 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In BDL rats, oral bioavailability of the Mrp2 substrate and food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) was elevated 2." | 1.32 | Consequences of bile duct obstruction on intestinal expression and function of multidrug resistance-associated protein 2. ( Dietrich, CG; Gartung, C; Geier, A; Lammert, F; Matern, S; Oude Elferink, RP; Roeb, E; Salein, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dietrich, CG | 1 |
| Geier, A | 1 |
| Salein, N | 1 |
| Lammert, F | 1 |
| Roeb, E | 1 |
| Oude Elferink, RP | 1 |
| Matern, S | 1 |
| Gartung, C | 1 |
1 other study available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Cholestasis
| Article | Year |
|---|---|
Consequences of bile duct obstruction on intestinal expression and function of multidrug resistance-associated protein 2.
Topics: Aged; Aged, 80 and over; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Bindi | 2004 |