2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Cancer of Pancreas in 6 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These featured dietary administration of PhIP at different dose levels and for different durations, and included intragastric dosing for a short period, or continuous dietary administration after initiation with other carcinogen, namely 3,2'-dimethyl-4-aminobiphenyl (DMAB) or 1,2-dimethylhydrazine (DMH)." | 1.31 | Organ differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreas. ( Asamoto, M; Futakuchi, M; Imaida, K; Kato, K; Shirai, T; Suzuki, S; Takahashi, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamagishi, M | 1 |
| Natsume, M | 1 |
| Osakabe, N | 1 |
| Nakamura, H | 1 |
| Furukawa, F | 1 |
| Imazawa, T | 1 |
| Nishikawa, A | 1 |
| Hirose, M | 3 |
| Shirai, T | 4 |
| Kato, K | 1 |
| Futakuchi, M | 3 |
| Takahashi, S | 2 |
| Suzuki, S | 1 |
| Imaida, K | 2 |
| Asamoto, M | 2 |
| Ogawa, K | 3 |
| Iwasaki, S | 1 |
| Esumi, H | 2 |
| Fukushima, S | 1 |
| Yamaguchi, T | 1 |
| Lin, C | 1 |
| Kimoto, N | 1 |
| Kono, T | 1 |
| Nishibe, S | 1 |
| Miki, T | 1 |
| Ochiai, M | 1 |
| Wakabayashi, K | 1 |
| Sugimura, T | 1 |
| Nagase, S | 1 |
| Nagao, M | 1 |
6 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Cancer of Pancreas
| Article | Year |
|---|---|
Effects of cacao liquor proanthocyanidins on PhIP-induced mutagenesis in vitro, and in vivo mammary and pancreatic tumorigenesis in female Sprague-Dawley rats.
Topics: Adenocarcinoma; Adenoma; Animals; Anthocyanins; Anticarcinogenic Agents; Antineoplastic Agents, Phyt | 2002 |
Organ differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreas.
Topics: 1,2-Dimethylhydrazine; Aminobiphenyl Compounds; Animals; Carcinogens; Colon; Colonic Neoplasms; DNA | 2002 |
Modification by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) of 3,2'-dimethyl-4-aminobiphenyl (DMAB)-induced rat pancreatic and intestinal tumorigenesis.
Topics: Adenocarcinoma; Aminobiphenyl Compounds; Animals; Body Weight; Carcinogens; Drug Synergism; Imidazol | 1998 |
Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats.
Topics: Animals; Biological Assay; Body Weight; Carcinogens; Carcinoma; Colonic Neoplasms; Diet; Drugs, Chin | 2000 |
Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animal Feed; Animals; Carcinogens; Colonic Neoplasms; DNA Add | 2002 |
Induction of intestinal adenocarcinomas by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Nagase analbuminemic rats.
Topics: Adenocarcinoma; Adenoma; Albumins; Animals; Carcinogenicity Tests; Cattle; Cooking; Food Contaminati | 1991 |