2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Cancer of Lung in 4 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because H and E sections of the myocardium from IQ-treated animals demonstrated inflammatory infiltrate and studies of IQ-DNA adducts in monkeys, by the 32P-postlabeling method, showed high levels of adducts in the heart a systematic study of cardiac pathologic changes associated with chronic administration of IQ was undertaken." | 1.29 | Studies on the carcinogenic and myocardial effects of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in nonhuman primates. ( Adamson, RH; Dalgard, DW; Farb, A; Snyderwine, EG; Sugimura, T; Takayama, S; Thorgeirsson, SS; Thorgeirsson, UP; Virmani, R, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lam, TK | 1 |
| Cross, AJ | 1 |
| Consonni, D | 1 |
| Randi, G | 1 |
| Bagnardi, V | 1 |
| Bertazzi, PA | 1 |
| Caporaso, NE | 1 |
| Sinha, R | 2 |
| Subar, AF | 1 |
| Landi, MT | 1 |
| Adamson, RH | 1 |
| Farb, A | 1 |
| Virmani, R | 1 |
| Snyderwine, EG | 1 |
| Thorgeirsson, SS | 1 |
| Takayama, S | 1 |
| Sugimura, T | 1 |
| Dalgard, DW | 1 |
| Thorgeirsson, UP | 1 |
| Dass, SB | 1 |
| Hammons, GJ | 1 |
| Bucci, TJ | 1 |
| Heflich, RH | 1 |
| Casciano, DA | 1 |
| Kulldorff, M | 1 |
| Swanson, CA | 1 |
| Curtin, J | 1 |
| Brownson, RC | 1 |
| Alavanja, MC | 1 |
4 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Cancer of Lung
| Article | Year |
|---|---|
Intakes of red meat, processed meat, and meat mutagens increase lung cancer risk.
Topics: Aged; Animals; Case-Control Studies; Cattle; Chickens; Female; Humans; Imidazoles; Italy; Lung Neopl | 2009 |
Studies on the carcinogenic and myocardial effects of 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in nonhuman primates.
Topics: Administration, Oral; Animals; Carcinogens; Cooking; DNA Adducts; Fibrosis; Heart; Hot Temperature; | 1995 |
Susceptibility of C57BL/6 mice to tumorigenicity induced by dimethylnitrosamine and 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine in the neonatal bioassay.
Topics: Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cytochrome P-450 CYP2E1; Dimethylnitr | 1998 |
Dietary heterocyclic amines and the risk of lung cancer among Missouri women.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cas | 2000 |