2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Bladder Cancer in 1 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results indicate that unconjugated N-OH-PhIP is not excreted in the urine after oral dosing with PhIP and that the two isomeric N-glucuronides of N-OH-PhIP, which are formed as major metabolites, are stable under acidic conditions." | 1.29 | Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis. ( Bartsch, H; Butler, MA; Friesen, MD; Ilett, KF; Kaderlik, RK; Kadlubar, F; Lin, D; Minchin, RF; Mulder, GJ; Teitel, CH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kadlubar, F | 1 |
| Kaderlik, RK | 1 |
| Mulder, GJ | 1 |
| Lin, D | 1 |
| Butler, MA | 1 |
| Teitel, CH | 1 |
| Minchin, RF | 1 |
| Ilett, KF | 1 |
| Friesen, MD | 1 |
| Bartsch, H | 1 |
1 other study available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Bladder Cancer
| Article | Year |
|---|---|
Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
Topics: Animals; Arylamine N-Acetyltransferase; Biotransformation; Carcinogens; Colonic Neoplasms; Cytochrom | 1995 |