2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Animal Mammary Carcinoma in 10 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 9 (90.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, M | 1 |
| Snyderwine, EG | 3 |
| Kawamori, T | 1 |
| Nakatsugi, S | 1 |
| Ohta, T | 1 |
| Sugimura, T | 2 |
| Wakabayashi, K | 1 |
| Takeshita, F | 1 |
| Ogawa, K | 1 |
| Asamoto, M | 2 |
| Shirai, T | 2 |
| Naito, A | 1 |
| Suzuki, A | 1 |
| Ueda, S | 1 |
| Nomoto, H | 1 |
| Toriyama-Baba, H | 1 |
| Tsuda, H | 1 |
| Kitamura, Y | 1 |
| Yamagishi, M | 1 |
| Okazaki, K | 1 |
| Furukawa, F | 1 |
| Imazawa, T | 1 |
| Nishikawa, A | 2 |
| Hirose, M | 2 |
| Josyula, S | 1 |
| He, YH | 1 |
| Ruch, RJ | 1 |
| Schut, HA | 2 |
| Shan, L | 1 |
| Rouhani, SA | 1 |
| Nagao, M | 1 |
| Ushijima, T | 1 |
| Watanabe, N | 1 |
| Okochi, E | 1 |
| Ochiai, M | 1 |
| Nakagama, H | 1 |
| Shibutani, M | 1 |
| Imai, T | 1 |
2 reviews available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Studies on mammary carcinogenesis induced by a heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, in mice and rats.
Topics: Adenocarcinoma; Animals; Carcinogens; DNA Damage; Female; Forecasting; Genes, p53; Hypoxanthine Phos | 2002 |
Mammary gland carcinogenesis by food-derived heterocyclic amines: metabolism and additional factors influencing carcinogenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Topics: Animals; Carcinogens; Diet; Female; Humans; Imidazoles; Mammary Neoplasms, Animal; Mammary Neoplasms | 2002 |
8 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Animal Mammary Carcinoma
| Article | Year |
|---|---|
H-ras oncogene mutations during development of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced rat mammary gland cancer.
Topics: Animals; Carcinogens; Cell Division; Codon; Female; Genes, ras; Imidazoles; Lasers; Mammary Neoplasm | 2002 |
Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, against PhIP-induced mammary carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinogens; Cyclooxygena | 2002 |
Mechanistic approach of contrasting modifying effects of caffeine on carcinogenesis in the rat colon and mammary gland induced with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Topics: Animals; Antimetabolites, Antineoplastic; Blotting, Western; Body Weight; Breast; Bromodeoxyuridine; | 2003 |
Preferential mammary carcinogenic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in human c-Ha-ras proto-oncogene transgenic rats.
Topics: Animals; Animals, Genetically Modified; Carcinogens; Cell Transformation, Neoplastic; DNA, Neoplasm; | 2004 |
Lack of enhancing effects of sodium nitrite on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in female Sprague-Dawley rats.
Topics: Animals; Body Weight; Carcinogens; Cell Death; Cell Proliferation; Drug Synergism; Female; Imidazole | 2006 |
Inhibition of DNA adduct formation of PhIP in female F344 rats by dietary conjugated linoleic acid.
Topics: Animals; Anticarcinogenic Agents; Blotting, Northern; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1 | 1998 |
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) modulates lactogenic hormone-mediated differentiation and gene expression in HC11 mouse mammary epithelial cells.
Topics: Animals; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Carcinogens; Caseins; DN | 2001 |
Chemoprevention of heterocyclic amine-induced mammary carcinogenesis in rats.
Topics: Animals; Antineoplastic Agents; Carcinogens; Female; Imidazoles; Incidence; Mammary Neoplasms, Anima | 2002 |