Page last updated: 2024-10-21

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Alzheimer Disease

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Alzheimer Disease in 1 studies

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Syeda, T1
Foguth, RM1
Llewellyn, E1
Cannon, JR1

Other Studies

1 other study available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Alzheimer Disease

ArticleYear
PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer's disease.
    Toxicology, 2020, 05-15, Volume: 437

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein

2020