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2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Aging

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Aging in 4 studies

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shan, L1
Yu, M1
Schut, HA1
Snyderwine, EG1
Sugiyama, S1
Takasawa, M1
Hayakawa, M1
Esumi, H1
Ozawa, T1
Paulsen, JE1
Fulland, RC1
Alexander, J1
Overvik, E1
Ochiai, M1
Hirose, M1
Sugimura, T1
Nagao, M1

Other Studies

4 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Aging

ArticleYear
Susceptibility of rats to mammary gland carcinogenesis by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) varies with age and is associated with the induction of differential gene expression.
    The American journal of pathology, 2004, Volume: 165, Issue:1

    Topics: Aging; Animals; Carcinogens; Cell Differentiation; Cell Division; Cluster Analysis; Disease Suscepti

2004
Detrimental effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a mutagenic agent, on mitochondrial respiration among various rat tissues.
    Biochemistry and molecular biology international, 1993, Volume: 30, Issue:5

    Topics: Aging; Animals; Diaphragm; Electron Transport; Electron Transport Complex II; Electron Transport Com

1993
Age-dependent induction of aberrant crypt foci in rat colon by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and azoxymethane.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:2

    Topics: Aging; Animals; Azoxymethane; Body Weight; Carcinogens; Choristoma; Colonic Neoplasms; Female; Imida

2000
The formation of heart DNA adducts in F344 rat following dietary administration of heterocyclic amines.
    Mutation research, 1991, Volume: 256, Issue:1

    Topics: Administration, Oral; Aging; Amines; Animals; Carbolines; Diet; DNA; DNA Damage; Heart; Imidazoles;

1991