2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Adenomatous Polyposis Coli, Familial in 2 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
Excerpt | Relevance | Reference |
---|---|---|
"Loss of function of the adenomatous polyposis coli (APC) gene product is an early and frequent event in human colorectal carcinogenesis." | 1.35 | High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation. ( Bellocq, D; Canlet, C; Martin, PG; Molina, J; Paris, A; Pierre, F; Rathahao, E; Taché, S, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Husøy, T | 1 |
Abramsson-Zetterberg, L | 1 |
Ølstørn, HB | 1 |
Paulsen, JE | 1 |
Alexander, J | 1 |
Bellocq, D | 1 |
Molina, J | 1 |
Rathahao, E | 1 |
Canlet, C | 1 |
Taché, S | 1 |
Martin, PG | 1 |
Pierre, F | 1 |
Paris, A | 1 |
2 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Adenomatous Polyposis Coli, Familial
Article | Year |
---|---|
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
Topics: Acrylamide; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Colchicine; Cyt | 2005 |
High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation.
Topics: Adenomatous Polyposis Coli; Animals; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; B | 2008 |