2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Adenomatous Polyposis Coli, Familial in 2 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loss of function of the adenomatous polyposis coli (APC) gene product is an early and frequent event in human colorectal carcinogenesis." | 1.35 | High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation. ( Bellocq, D; Canlet, C; Martin, PG; Molina, J; Paris, A; Pierre, F; Rathahao, E; Taché, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Husøy, T | 1 |
| Abramsson-Zetterberg, L | 1 |
| Ølstørn, HB | 1 |
| Paulsen, JE | 1 |
| Alexander, J | 1 |
| Bellocq, D | 1 |
| Molina, J | 1 |
| Rathahao, E | 1 |
| Canlet, C | 1 |
| Taché, S | 1 |
| Martin, PG | 1 |
| Pierre, F | 1 |
| Paris, A | 1 |
2 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Adenomatous Polyposis Coli, Familial
| Article | Year |
|---|---|
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
Topics: Acrylamide; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Colchicine; Cyt | 2005 |
High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation.
Topics: Adenomatous Polyposis Coli; Animals; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; B | 2008 |