2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Adenoma, Prostatic in 2 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, benign prostatic hyperplasia tissues, obtained by transurethral resection or radical retropubic prostatectomy from UK-resident individuals (n = 18), were examined for CYP1 expression and for their ability, in short-term organ culture, to metabolically activate carcinogens found in cooked meat." | 1.31 | Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue. ( Grover, PL; Hewer, A; Martin, FL; Muir, GH; Phillips, DH; Williams, JA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shirai, T | 1 |
| Sano, M | 1 |
| Tamano, S | 1 |
| Takahashi, S | 1 |
| Hirose, M | 1 |
| Futakuchi, M | 1 |
| Hasegawa, R | 1 |
| Imaida, K | 1 |
| Matsumoto, K | 1 |
| Wakabayashi, K | 1 |
| Sugimura, T | 1 |
| Ito, N | 1 |
| Williams, JA | 1 |
| Martin, FL | 1 |
| Muir, GH | 1 |
| Hewer, A | 1 |
| Grover, PL | 1 |
| Phillips, DH | 1 |
2 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Adenoma, Prostatic
| Article | Year |
|---|---|
The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods.
Topics: Animals; Carcinogens; Imidazoles; Male; Neoplasms, Experimental; Prostate; Prostatic Hyperplasia; Pr | 1997 |
Metabolic activation of carcinogens and expression of various cytochromes P450 in human prostate tissue.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-4 | 2000 |