2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine has been researched along with Adenocarcinoma Of Kidney in 3 studies
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine: mutagen from fried ground beef; structure given in first source
PhIP : An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in cooked meat and fish.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These associations may be modified by genetic susceptibility to RCC." | 1.43 | Gene-environment interaction of genome-wide association study-identified susceptibility loci and meat-cooking mutagens in the etiology of renal cell carcinoma. ( Daniel, CR; Karam, JA; Matin, SF; Melkonian, SC; Tannir, NM; Wood, CG; Wu, X; Ye, Y, 2016) |
| "The evidence for meat intake and renal cell carcinoma (RCC) risk is inconsistent." | 1.38 | Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma. ( Chow, WH; Cross, AJ; Daniel, CR; Graubard, BI; Hollenbeck, AR; Park, Y; Rothman, N; Sinha, R; Ward, MH, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, IJ | 1 |
| Chen, SC | 1 |
| Yen, MC | 1 |
| Wu, YH | 1 |
| Hung, CH | 1 |
| Kuo, PL | 1 |
| Melkonian, SC | 1 |
| Daniel, CR | 2 |
| Ye, Y | 1 |
| Tannir, NM | 1 |
| Karam, JA | 1 |
| Matin, SF | 1 |
| Wood, CG | 1 |
| Wu, X | 1 |
| Cross, AJ | 1 |
| Graubard, BI | 1 |
| Park, Y | 1 |
| Ward, MH | 1 |
| Rothman, N | 1 |
| Hollenbeck, AR | 1 |
| Chow, WH | 1 |
| Sinha, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| NCI-AARP Diet and Health Study[NCT00340015] | 566,401 participants (Actual) | Observational | 1995-10-24 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine and Adenocarcinoma Of Kidney
| Article | Year |
|---|---|
6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential.
Topics: Carcinoma, Renal Cell; Catechols; Cell Line, Tumor; Humans; Imidazoles; Kidney Neoplasms; Neoplasm M | 2019 |
Gene-environment interaction of genome-wide association study-identified susceptibility loci and meat-cooking mutagens in the etiology of renal cell carcinoma.
Topics: Carcinoma, Renal Cell; Case-Control Studies; Disease Susceptibility; Female; Gene-Environment Intera | 2016 |
Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinoma.
Topics: Benzo(a)pyrene; Carcinoma, Renal Cell; Cooking; Diet; Female; Humans; Imidazoles; Incidence; Male; M | 2012 |